All patients require long-term follow-up using periodic brain magnetic resonance imaging scans. Regular endocrinologic follow-up is required in all patients with craniopharyngioma; ophthalmology follow-up postoperatively and at subsequent periodic intervals is also recommended.[8]Halac I, Zimmerman D. Endocrine manifestations of craniopharyngioma. Childs Nerv Syst. 2005 Aug;21(8-9):640-8.
https://link.springer.com/article/10.1007%2Fs00381-005-1246-x
http://www.ncbi.nlm.nih.gov/pubmed/16047216?tool=bestpractice.com
[21]Rajan B, Ashley S, Thomas DG, et al. Craniopharyngioma: improving outcome by early recognition and treatment of acute complications. Int J Radiat Oncol Biol Phys. 1997 Feb 1;37(3):517-21.
http://www.ncbi.nlm.nih.gov/pubmed/9112447?tool=bestpractice.com
[24]Sorva R, Heiskanen O, Perheetupa J. Craniopharyngioma surgery in children: endocrine and visual outcome. Childs Nerv Syst. 1988 Apr;4(2):97-9.
http://www.ncbi.nlm.nih.gov/pubmed/3401877?tool=bestpractice.com
[49]Müller HL. Consequences of craniopharyngioma surgery in children. J Clin Endocrinol Metab. 2011 Jul;96(7):1981-91.
https://academic.oup.com/jcem/article/96/7/1981/2833879
http://www.ncbi.nlm.nih.gov/pubmed/21508127?tool=bestpractice.com
[50]Poretti A, Grotzer MA, Ribi K, et al. Outcome of craniopharyngioma in children: long-term complications and quality of life. Dev Med Child Neurol. 2004 Apr;46(4):220-9.
http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8749.2004.tb00476.x/pdf
http://www.ncbi.nlm.nih.gov/pubmed/15077699?tool=bestpractice.com
[64]Dekkers OM, Biermasz NR, Smit JW, et al. Quality of life in treated adult craniopharyngioma patients. Eur J Endocrinol. 2006 Mar;154(3):483-9.
https://eje.bioscientifica.com/view/journals/eje/154/3/1540483.xml
http://www.ncbi.nlm.nih.gov/pubmed/16498063?tool=bestpractice.com
Most patients are followed every 6 to 12 months, recognizing that most recurrences occur relatively early (within the first several years). Patients with complications following treatment (hypothalamic syndrome, seizures, cognitive loss) may be followed on a more frequent basis. Patients are best managed by a multidisciplinary team, which may include a pediatrician or internist/primary care physician, endocrinologist, ophthalmologist, radiation oncologist, and neurosurgeon. Coordination of care may be challenging given the multiple specialties involved and is best managed at tertiary medical centers. Ideally, patients and families need a single contact person (physician or nurse), as care may seem fragmented and overly complicated. Having simple, direct lines of communication provides patients and families with a sense of continuity of care, and improves care in a complex condition.