Complications

Complication
Timeframe
Likelihood
short term
low

Deposition of bilirubin in the basal ganglia of the neonate. Avoided by monitoring bilirubin levels closely and instituting phototherapy/exchange transfusion appropriately.

long term
high

Some studies have found increased incidence or earlier onset of cataracts in people with G6PD deficiency.[11][12][21][37]

Cataracts

variable
low

In the rare patient with a class I variant and chronic hemolysis, gallstones can occur.

variable
low

In vitro data, observations in neonates and trauma patients, and animal studies show possible increased susceptibility to infection.[48][49] This may be explained by the altered cytokine response and impaired neutrophil function in people with G6PD deficiency.[11][21]

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