Epidemiology

In the US, Europe, and Japan, estimated incidence of chronic granulomatous disease (CGD) is between 1 in 200,000 and 1 in 250,000 of live births.[3] [4][13][14] Males are predominantly affected, as the majority of cases are X-linked (approximately 65% to 70% of cases).[3][4][15][16] Just under 40% of patients in the US are diagnosed before the age of 1, with the majority of patients diagnosed by age 5.[3] The condition may remain undiagnosed until the adult years, with the majority of late diagnoses having autosomal recessive forms of the disease.[3][4]

The United States Immunodeficiency Network (USIDNET) has an online registry of patients with primary immunodeficiency diseases including CGD. The United States Immunodeficiency Network Opens in new window

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