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Last reviewed: 16 Mar 2025
Last updated: 20 Dec 2024

Summary

Definition

History and exam

Key diagnostic factors

  • coronary artery disease
  • tachycardia
  • hypotension

Other diagnostic factors

  • weak pulse
  • syncope
  • presyncope
  • airway compromise
  • impaired consciousness
  • lightheadedness
  • dizziness
  • diminished responsiveness
  • chest discomfort
  • dyspnea
  • asymptomatic

Risk factors

  • coronary artery disease
  • acute myocardial infarction
  • left ventricular systolic dysfunction
  • hypertrophic cardiomyopathy
  • long QT syndrome
  • short QT syndrome
  • Brugada syndrome
  • sleep-disordered breathing (SDB)
  • family history of sudden death
  • mental or physical stress
  • ventricular pre-excitation
  • arrhythmogenic right ventricular cardiomyopathy
  • electrolyte imbalance
  • drug toxicity
  • Chagas disease and other cardiomyopathies

Diagnostic tests

1st tests to order

  • ECG
  • transthoracic echocardiogram
  • electrolytes
  • troponin I

Tests to consider

  • cardiac catheterization
  • cardiac MRI
  • electrophysiologic (EP) study
  • genetic testing

Treatment algorithm

Contributors

Authors

Sei Iwai, MD, FACC, FHRS

Professor of Clinical Medicine

New York Medical College

Section Chief, Cardiac Electrophysiology

Westchester Medical Center Health Network

Valhalla

NY

Disclosures

SI is an author of some references cited in this topic.

Acknowledgements

Professor Sei Iwai would like to gratefully acknowledge Dr Kenneth Stein and Dr Richard Keating, previous contributors to this topic.

Disclosures

KS declares he is an employee of and shareholder in Boston Scientific, a manufacturer of implantable cardioverter defibrillators and ablation catheters. RK declares that he has no competing interests.

Peer reviewers

Suneet Mittal, MD

Director

Electrophysiology Laboratory

The St. Luke's-Roosevelt Hospital Center

New York

NY

Disclosures

SM declares that he has no competing interests.

Kenneth A. Ellenbogen, MD

Kontos Professor of Cardiology

Medical College of Virginia

Richmond

VA

Disclosures

KAE declares that he has no competing interests.

Kim Rajappan, MA, MD, MRCP

Consultant Cardiologist and Electrophysiologist

Cardiac Department

John Radcliffe Hospital

Oxford

UK

Disclosures

KR declares that she has no competing interests.

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