The longer it takes to diagnose and treat testicular torsion, the greater the risk that the patient will develop tissue necrosis, decreased tissue viability, decreased spermatogenesis, and possible infertility. Testicular salvage rates decline as the duration of symptoms increases, with greatly reduced testicular salvage at 24 hours and consistently poor results beyond 48 hours.[19]Leslie JA, Cain MP. Pediatric urologic emergencies and urgencies. Pediatr Clin North Am. 2006 Jun;53(3):513-27.
http://www.ncbi.nlm.nih.gov/pubmed/16716794?tool=bestpractice.com
[22]Morin OA, Carr MG, Holcombe JM, et al. Optimal predictor of gonadal viability in testicular torsion: Time to treat versus duration of symptoms. J Surg Res. 2019 Dec;244:574-578.
https://www.doi.org/10.1016/j.jss.2019.06.033
http://www.ncbi.nlm.nih.gov/pubmed/31357158?tool=bestpractice.com
Recurrent torsion may develop many years later in patients with a past history of testicular fixation, regardless of whether absorbable or nonabsorbable sutures were used.[58]Mor Y, Pinthus JH, Nadu A, et al. Testicular fixation following torsion of the spermatic cord - does it guarantee prevention of recurrent torsion events? J Urol. 2006 Jan;175(1):171-3.
http://www.ncbi.nlm.nih.gov/pubmed/16406900?tool=bestpractice.com
A heightened level of suspicion for these patients is important to prevent testicular damage.
The traumatic experience of losing a testicle can be mitigated by offering a prosthetic device, usually a saline-filled silicone implant, which can improve cosmetic appearance and perhaps the patient's psychological well-being. Testosterone-releasing prosthetic devices have shown success in animal models.[54]Bodiwala D, Summerton DJ, Terry TR. Testicular prostheses: development and modern usage. Ann R Coll Surg Engl. 2007 May;89(4):349-53.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963594/pdf/rcse8904-349.pdf
http://www.ncbi.nlm.nih.gov/pubmed/17535609?tool=bestpractice.com
[55]Chen HX, Yang S, Ning Y, et al. Novel double-layer Silastic testicular prosthesis with controlled release of testosterone <i>in vitro</i>, and its effects on castrated rats. Asian J Androl. 2017 Jul-Aug;19(4):433-438.
https://www.doi.org/10.4103/1008-682X.175786
http://www.ncbi.nlm.nih.gov/pubmed/27174160?tool=bestpractice.com