Primary prevention

The only preventive measure available is to perform genetic analysis on couples before they become pregnant.

Secondary prevention

Secondary prevention should be aimed at preventing patients from acquiring disease-modifying infections and processes that may lead to disease progression. One systematic review found low-quality evidence that segregation can prevent infection spread, and noted the ethical difficulty researching this topic.[194]​ For example, patients with CF who are colonized with Burkholderia cepacia complex should be isolated from those without B cepacia because of the potential for patient-to-patient transmission.

Frequent hand cleaning, wearing gowns and gloves, and keeping people with CF a safe distance from each other are important infection control strategies for Pseudomonas.[195][196]​​​ Immunizations should be offered to all individuals who are eligible, according to local or national guidance (e.g., influenza and COVID-19).[148][197]​​

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