Case history
Case history
A 70-year-old man presents with generalized fatigue that has slowly progressed over several months. On physical exam, the patient has pale mucous membranes and mild tachycardia. The remainder of the exam is unremarkable.
Other presentations
Patients are often asymptomatic at presentation, and MDS is diagnosed incidentally following routine laboratory tests. If symptoms develop they are usually nonspecific and related to anemia (e.g. weakness, fatigue, decreased exercise tolerance, lightheadedness, angina).[4] Less common symptoms are those related to thrombocytopenia (e.g. easy bruising, bleeding) and neutropenia (e.g. infections).[5] Occasionally, MDS can present with autoimmune abnormalities, such as vasculitis, connective tissue disease, and inflammatory arthritis.[6][7][8]
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