Otitis media with effusion (OME) is a common childhood illness, particularly in children aged under 5 years.[2]Rosenfeld RM, Shin JJ, Schwartz SR, et al. Clinical practice guideline: otitis media with effusion (update). Otolaryngol Head Neck Surg. 2016 Feb;154(1 suppl):S1-41.
https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1177/0194599815623467
http://www.ncbi.nlm.nih.gov/pubmed/26832942?tool=bestpractice.com
It can be found in over 50% of children aged under 1 year and 60% of children aged under 2 years.[1]Simon F, Haggard M, Rosenfeld RM, et al. International consensus (ICON) on management of otitis media with effusion in children. Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Feb;135(1s):S33-9.
https://www.sciencedirect.com/science/article/pii/S187972961830005X
http://www.ncbi.nlm.nih.gov/pubmed/29398506?tool=bestpractice.com
[5]Casselbrant ML. Epidemiology. In: Rosenfeld RM, Bluestone CD, ed. Evidence-based otitis media. Decker BC: Hamilton ON; 1999.177–236. Approximately 2.2 million new cases of OME are diagnosed annually in the United States.[2]Rosenfeld RM, Shin JJ, Schwartz SR, et al. Clinical practice guideline: otitis media with effusion (update). Otolaryngol Head Neck Surg. 2016 Feb;154(1 suppl):S1-41.
https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1177/0194599815623467
http://www.ncbi.nlm.nih.gov/pubmed/26832942?tool=bestpractice.com
In one study of primary school children in western Sicily screened for OME, the condition was identified in 143 out of 2097 children.[6]Martines F, Bentivegna D, Di Piazza F, et al. The point prevalence of otitis media with effusion among primary school children in Western Sicily. Eur Arch Otorhinolaryngol. 2010 May;267(5):709-14.
http://www.ncbi.nlm.nih.gov/pubmed/19859723?tool=bestpractice.com
The overall prevalence of OME was found to be 6.8%, with a maximum prevalence of 12.9% between ages 5 and 6 years. The prevalence of OME decreased with increasing age of the child.[6]Martines F, Bentivegna D, Di Piazza F, et al. The point prevalence of otitis media with effusion among primary school children in Western Sicily. Eur Arch Otorhinolaryngol. 2010 May;267(5):709-14.
http://www.ncbi.nlm.nih.gov/pubmed/19859723?tool=bestpractice.com
However, as OME can be asymptomatic it may be difficult to detect and truly quantify.
The prevalence of OME is higher in children with cleft lip and palate than in children without.[7]Flynn T, Möller C, Jönsson R, et al. The high prevalence of otitis media with effusion in children with cleft lip and palate as compared to children without clefts. Int J Pediatr Otorhinolaryngol. 2009 Oct;73(10):1441-6.
https://www.sciencedirect.com/science/article/abs/pii/S0165587609003863?via%3Dihub
http://www.ncbi.nlm.nih.gov/pubmed/19709760?tool=bestpractice.com
[2]Rosenfeld RM, Shin JJ, Schwartz SR, et al. Clinical practice guideline: otitis media with effusion (update). Otolaryngol Head Neck Surg. 2016 Feb;154(1 suppl):S1-41.
https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1177/0194599815623467
http://www.ncbi.nlm.nih.gov/pubmed/26832942?tool=bestpractice.com
OME continues to be prevalent in children after cleft palate repair.[8]Téblick S, Ruymaekers M, Van de Casteele E, et al. Effect of cleft palate closure technique on speech and middle ear outcome: a systematic review. J Oral Maxillofac Surg. 2019 Feb;77(2):405.e1-405.e15.
https://www.joms.org/article/S0278-2391(18)31099-1/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/30367844?tool=bestpractice.com
The prevalence of OME is also higher in children with Down syndrome.[2]Rosenfeld RM, Shin JJ, Schwartz SR, et al. Clinical practice guideline: otitis media with effusion (update). Otolaryngol Head Neck Surg. 2016 Feb;154(1 suppl):S1-41.
https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1177/0194599815623467
http://www.ncbi.nlm.nih.gov/pubmed/26832942?tool=bestpractice.com
One retrospective cross-sectional analysis found a peak in prevalence in children with Down syndrome at age 1 year (66.7%), with a second peak at age 6 to 7 years (60%).[9]Maris M, Wojciechowski M, Van de Heyning P, et al. A cross-sectional analysis of otitis media with effusion in children with Down syndrome. Eur J Pediatr. 2014 Oct;173(10):1319-25.
http://www.ncbi.nlm.nih.gov/pubmed/24816633?tool=bestpractice.com