The incidence in the US is reported to be 2.6 cases per 100,000 women per year.[8]Curhan GC, Speizer FE, Hunter DJ, et al. Epidemiology of interstitial cystitis: a population based study. J Urol. 1999 Feb;161(2):549-52.
http://www.ncbi.nlm.nih.gov/pubmed/9915446?tool=bestpractice.com
The estimated prevalence is around 45 per 100,000 women and 8 per 100,000 men, but prevalence data conflict depending on the country of origin and the criteria used for diagnosis.[9]Patnaik SS, Laganà AS, Vitale SG, et al. Etiology, pathophysiology and biomarkers of interstitial cystitis/painful bladder syndrome. Arch Gynecol Obstet. 2017 Jun;295(6):1341-59.
http://www.ncbi.nlm.nih.gov/pubmed/28391486?tool=bestpractice.com
In one large study in the US, 2.70% to 6.53% of women had symptoms of IC/BPS (depending on whether high specificity or high sensitivity criteria were used).[10]Berry SH, Elliott MN, Suttorp M, et al. Prevalence of symptoms of bladder pain syndrome/interstitial cystitis among adult females in the United States. J Urol. 2011 Aug;186(2):540-4.
http://www.ncbi.nlm.nih.gov/pubmed/21683389?tool=bestpractice.com
While 87.1% reported consulting a physician about their symptoms, only 9.9% of women had been diagnosed with IC/BPS, suggesting the condition may be underdiagnosed.[10]Berry SH, Elliott MN, Suttorp M, et al. Prevalence of symptoms of bladder pain syndrome/interstitial cystitis among adult females in the United States. J Urol. 2011 Aug;186(2):540-4.
http://www.ncbi.nlm.nih.gov/pubmed/21683389?tool=bestpractice.com
One managed care review asserts a female-to-male ratio of 5:1.[11]Clemens JQ, Meenan RT, Rosetti MC, et al. Prevalence and incidence of interstitial cystitis in a managed care population. J Urol. 2005 Jan;173(1):98-102.
http://www.ncbi.nlm.nih.gov/pubmed/15592041?tool=bestpractice.com
The age range with the highest prevalence is 40 to 60 years.[11]Clemens JQ, Meenan RT, Rosetti MC, et al. Prevalence and incidence of interstitial cystitis in a managed care population. J Urol. 2005 Jan;173(1):98-102.
http://www.ncbi.nlm.nih.gov/pubmed/15592041?tool=bestpractice.com
In a survey of adults ages 40-79 years in South Korea, the prevalence of IC/BPS-like symptoms was 21.4% among women and 10.7% among men.[12]Lee JW, Yoo KH, Choi H. Prevalence of Bladder Pain Syndrome-like Symptoms: a Population-based Study in Korea. J Korean Med Sci. 2021 Nov 29;36(46):e293.
https://www.doi.org/10.3346/jkms.2021.36.e293
http://www.ncbi.nlm.nih.gov/pubmed/34845871?tool=bestpractice.com
Some studies suggest IC/BPS is more common among white people.[10]Berry SH, Elliott MN, Suttorp M, et al. Prevalence of symptoms of bladder pain syndrome/interstitial cystitis among adult females in the United States. J Urol. 2011 Aug;186(2):540-4.
http://www.ncbi.nlm.nih.gov/pubmed/21683389?tool=bestpractice.com
[13]Dallas KB, Bresee C, De Hoedt A, et al. Demographic differences and disparities in the misdiagnosis of interstitial cystitis/bladder pain syndrome in a national cohort of VA patients. Urology. 2022 May;163:22-8.
http://www.ncbi.nlm.nih.gov/pubmed/34348123?tool=bestpractice.com