Case history

Case history #1

A 38-year-old man presents to his primary care physician complaining of generalized weakness, epistaxis, mouth ulcers, and weight loss. He has an unremarkable past medical history and takes no medications. Physical examination reveals mild pallor and petechial hemorrhages over his lower limbs. He has multiple widespread small lymph nodes that are palpable, and mild splenomegaly.

Case history #2

A 4-year-old girl presents with lethargy, dyspnea, fever, and bruising. On examination she has hepatosplenomegaly. Chest radiograph shows a mediastinal mass and pleural effusion.

Other presentations

Other presentations of ALL include pancytopenia, eosinophilia, isolated renal failure, pulmonary nodules, bone marrow necrosis, pericardial effusion, superior vena cava obstruction, hypoglycemia, joint pain, mental status changes, headaches, chin numbness, and skin nodules.[1][8]

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