Syndrome of inappropriate antidiuretic hormone

No evidence is available that supports screening for SIADH. However, high-risk groups such as older adults, those on offending drugs, and postoperative patients would undoubtedly benefit from baseline serum sodium levels being performed. These should be checked yearly in older patients, pre- and postoperation in ambulatory hospitalized surgical patients, especially if hypotonic fluids are administered, and 1 to 2 weeks after starting an offending drug. If antidepressant medications are started, selective serotonin-reuptake inhibitors in particular and especially in high risk groups, the patient is at most risk of developing hyponatremia in the first 3 months of treatment. Electrolytes should be monitored closely during this period.[20]Lien YH. Antidepressants and hyponatremia. Am J Med. 2018 Jan;131(1):7-8. http://www.amjmed.com/article/S0002-9343(17)30920-8/fulltext