Tests

1st tests to order

ECG

Test
Result
Test

Essential for the clinical diagnosis of atrial flutter.

In the typical form (counterclockwise atrial flutter), negatively directed saw-tooth atrial deflections (f waves) in leads II, III, and aVF, and positive deflections in V1 with atrial rates of 240 to 320 bpm are seen.

2:1 atrioventricular block is usually present in the typical form, resulting in the characteristic ventricular rate of 150 bpm. However, variable block may occur, leading to an irregular rate.

In the reverse typical form (clockwise isthmus-dependent flutter), positive flutter waves in leads II, III, and aVF, and negative flutter waves in lead V1 are seen.

Atypical flutter has an ECG pattern of continuous undulation of the atrial complex, not meeting criteria for typical or reverse typical flutter, with atrial rates >240 bpm.

Carotid massage or giving adenosine during ECG recording generally slows the ventricular rate to allow better visualization of the flutter waves if the diagnosis is not clear.

[Figure caption and citation for the preceding image starts]: Typical atrial flutter with variable (3 to 4:1) blockFrom the collection of Dr K.C. Wu [Citation ends].com.bmj.content.model.Caption@6176bf20[Figure caption and citation for the preceding image starts]: Close-up images of leads V1, II, III, aVF demonstrating the features of typical atrial flutter: positive saw-tooth deflections in lead V1 and negative deflections in leads II, III, aVF (arrows)From the collection of Dr K.C. Wu [Citation ends].com.bmj.content.model.Caption@6712be32[Figure caption and citation for the preceding image starts]: Reverse typical atrial flutterFrom: Waldo AL. Heart. 2000 Aug;84(2):227-32; used with permission [Citation ends].com.bmj.content.model.Caption@322378d9[Figure caption and citation for the preceding image starts]: Selected leads from a patient with reverse typical atrial flutter confirmed at electrophysiologic study. The atrial deflections are negative in lead V1 and positive in leads II, III, aVF (arrows)Adapted from: Waldo AL. Heart. 2000 Aug;84(2):227-32; used with permission [Citation ends].com.bmj.content.model.Caption@19240fe5[Figure caption and citation for the preceding image starts]: Atypical flutter with right bundle branch blockFrom the collection of Dr K.C. Wu [Citation ends].com.bmj.content.model.Caption@3af7b389[Figure caption and citation for the preceding image starts]: Close up of leads II, III, V1 showing the continuously undulating pattern of atrial deflections not fitting the criteria for typical or reverse typical atrial flutterFrom the collection of Dr K.C. Wu [Citation ends].com.bmj.content.model.Caption@483ce5ec

Result

changes diagnostic of typical, reverse typical, or atypical atrial flutter

thyroid function tests

Test
Result
Test

To rule out underlying thyroid disease.

Result

normal; abnormal if underlying thyroid disease is present

serum electrolytes

Test
Result
Test

Electrolyte abnormalities are generally not the sole cause of atrial flutter, but imbalances should be checked and corrected.

Result

normal; abnormal if underlying electrolyte disturbances are present

Investigations to avoid

imaging stress tests

Recommendations
Rationale
Recommendations

Avoid routine imaging stress tests for the workup of palpitations or presyncope.[21]

Rationale

If there are no symptoms or signs of cardiovascular disease then cardiac imaging beyond a transthoracic echocardiogram is rarely needed.[21]

coronary CT angiography

Recommendations
Rationale
Recommendations

Avoid routine coronary CT angiography for the workup of palpitations or presyncope.[21]

Rationale

If there are no symptoms or signs of cardiovascular disease then cardiac imaging beyond a transthoracic echocardiogram is rarely needed.[21]

Tests to consider

pulmonary function tests

Test
Result
Test

Should be ordered if there is clinical suspicion of lung disease as a cause.

Result

normal; abnormal if underlying lung disease is present

CXR

Test
Result
Test

Should be ordered if there is clinical suspicion of lung disease as a cause.

Result

normal; may be abnormal if underlying lung disease is present

digitalis level

Test
Result
Test

Rarely a cause of atrial flutter, but digitalis toxicity may be considered in patients taking digitalis drugs (e.g., digoxin).

Result

normal; elevated in digitalis toxicity

cardiac enzymes

Test
Result
Test

May be considered if acute myocardial infarction (MI) is suspected.

Result

normal; elevated in MI

spiral CT with pulmonary embolism protocol

Test
Result
Test

May be considered if pulmonary emboli are suspected.

Result

normal; direct visualization of thrombus in a pulmonary artery in pulmonary embolism

transthoracic echocardiogram

Test
Result
Test

Atrial sizes can be measured.

Can also assess for valvular disease, ventricular function, and pericardial disease.

Right ventricular systolic pressures (RVSP) can also be measured.

Elevated RVSP indicates the presence of pulmonary hypertension, which can be seen in pulmonary processes.

Result

possible structural heart disease

atrial electrogram recording

Test
Result
Test

Recorded by postsurgical epicardial leads, dual chamber pacemaker, or esophageal lead.

Can help visualize flutter waves when the diagnosis is not clear.

Result

flutter waves

electrophysiologic studies

Test
Result
Test

Requires the input of electrophysiologists.

May be required for diagnosis, mapping of the critical isthmus (i.e., the cavotricuspid isthmus), and therapeutic ablation.

Result

map of reentrant circuit

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