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Last reviewed: 16 Mar 2025
Last updated: 10 Dec 2024

Summary

Definition

History and exam

Key diagnostic factors

  • worsening heart failure or pulmonary symptoms
  • jugular venous pulsations with rapid flutter waves

Other diagnostic factors

  • palpitations
  • fatigue or lightheadedness
  • chest pain
  • dyspnea
  • syncope
  • hypotension
  • embolic events

Risk factors

  • increasing age
  • valvular dysfunction
  • atrial septal defects
  • atrial dilation
  • recent cardiac or thoracic procedures
  • surgical or postablation scarring of atria
  • heart failure
  • hyperthyroidism
  • COPD
  • asthma
  • pneumonia
  • antiarrhythmic drugs for atrial fibrillation
  • diabetes
  • digitalis use
  • male sex
  • congenital or lone atrial flutter

Diagnostic tests

1st tests to order

  • ECG
  • thyroid function tests
  • serum electrolytes

Investigations to avoid

  • imaging stress tests
  • coronary CT angiography

Tests to consider

  • pulmonary function tests
  • CXR
  • digitalis level
  • cardiac enzymes
  • spiral CT with pulmonary embolism protocol
  • transthoracic echocardiogram
  • atrial electrogram recording
  • electrophysiologic studies

Treatment algorithm

Contributors

Authors

Katherine C. Wu, MD, FACC

Associate Professor of Medicine

Johns Hopkins University

School of Medicine

Baltimore

MD

Disclosures

KCW declares that she has no competing interests.

Peer reviewers

Richard C. Wu, MD

Associate Professor of Medicine

Director

Cardiac Electrophysiology Laboratory

UT Southwestern Medical Center

University Hospital

St. Paul

Dallas

TX

Disclosures

RCW declares that he has no competing interests.

Reginald Ho, MD

Clinical Assistant Professor

Department of Medicine

Thomas Jefferson University Hospital

Philadelphia

PA

Disclosures

RH declares that he has no competing interests.

George Juang, MD, FACC

Director of Electrophysiology

Long Island Arrhythmia Center

Mineola

NY

Disclosures

GJ declares that he has no competing interests.

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