In the US, guidelines recommend that infra-/juxtarenal AAAs measuring 4.0 to 4.9 cm in diameter with ultrasonography/computed tomography (CT) should be monitored every 6 to 12 months.[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
Once larger than 4.5 cm in women and 5 cm in men, these guidelines recommend surveillance every 6 months.[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
AAAs <3.9 cm can be monitored with ultrasonography every 2 to 3 years.[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
The American College of Radiology recommends that color duplex doppler ultrasound, CT of the abdomen and pelvis with contrast, and magnetic resonance angiography (MRA) are all appropriate imaging modalities for surveillance of patients with asymptomatic AAA.[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
[293]Expert Panel on Vascular Imaging; Collard M, Sutphin PD, et al. ACR Appropriateness Criteria: abdominal aortic aneurysm follow-up (without repair). J Am Coll Radiol. 2019 May;16(5s):S2-S6.
https://www.doi.org/10.1016/j.jacr.2019.02.005
http://www.ncbi.nlm.nih.gov/pubmed/31054747?tool=bestpractice.com
There is also evidence to suggest that color duplex doppler ultrasound may be as sensitive as CT for detecting endoleaks post EVAR and could be utilized as a safe and effective alternative which avoids exposing the patients to further radiation.[294]Brazzelli M, Hernández R, Sharma P, et al. Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation. Health Technol Assess. 2018 Dec;22(72):1-220.
https://www.doi.org/10.3310/hta22720
http://www.ncbi.nlm.nih.gov/pubmed/30543179?tool=bestpractice.com
[295]Harky A, Zywicka E, Santoro G, et al. Is contrast-enhanced ultrasound (CEUS) superior to computed tomography angiography (CTA) in detection of endoleaks in post-EVAR patients? A systematic review and meta-analysis. J Ultrasound. 2019 Mar;22(1):65-75.
https://www.doi.org/10.1007/s40477-019-00364-7
http://www.ncbi.nlm.nih.gov/pubmed/30771104?tool=bestpractice.com
[296]de Mik SML, Geraedts ACM, Ubbink DT, et al. Effect of imaging surveillance after endovascular aneurysm repair on reinterventions and mortality: a systematic review and meta-analysis. J Endovasc Ther. 2019 Aug;26(4):531-41.
https://www.doi.org/10.1177/1526602819852085
http://www.ncbi.nlm.nih.gov/pubmed/31140361?tool=bestpractice.com
A systematic review and meta-analysis of individual patient data concluded that surveillance intervals of 2 years for 3.0- to 4.4-cm AAAs, and 6 months for 4.5- to 5.4-cm AAAs, are safe and cost-effective.[131]Thompson S, Brown L, Sweeting M, et al; RESCAN Collaborators. Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost-effectiveness. Health Technol Assess. 2013 Sep;17(41):1-118.
https://www.journalslibrary.nihr.ac.uk/hta/hta17410/#/full-report
http://www.ncbi.nlm.nih.gov/pubmed/24067626?tool=bestpractice.com
Analysis of AAA growth and rupture rates indicated that, in order to maintain a AAA rupture risk <1%, an 8.5-year surveillance interval is required for men with baseline AAA diameter of 3.0 cm.[131]Thompson S, Brown L, Sweeting M, et al; RESCAN Collaborators. Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost-effectiveness. Health Technol Assess. 2013 Sep;17(41):1-118.
https://www.journalslibrary.nihr.ac.uk/hta/hta17410/#/full-report
http://www.ncbi.nlm.nih.gov/pubmed/24067626?tool=bestpractice.com
The corresponding estimated surveillance interval for men with an initial aneurysm diameter of 5.0 cm was 17 months. Despite having similar growth rates of small aneurysms, rupture rates were 4 times greater in women than in men.[131]Thompson S, Brown L, Sweeting M, et al; RESCAN Collaborators. Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost-effectiveness. Health Technol Assess. 2013 Sep;17(41):1-118.
https://www.journalslibrary.nihr.ac.uk/hta/hta17410/#/full-report
http://www.ncbi.nlm.nih.gov/pubmed/24067626?tool=bestpractice.com
Surveillance programs and criteria for considering surgery need to be tailored for women with opportunistically detected AAA.
The European Society for Vascular Surgery (ESVS) recommends incorporation of subaneurysmal aortas (2.5 to 2.9 cm) into AAA surveillance recommendations since long-term cohort studies show that most subaneurysmal aortas eventually progress to an AAA of which a substantial proportion will reach the diameter threshold for consideration of repair.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
Surveillance decisions should take into account life expectancy, suitability for future repair, and patient preferences.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
Post repair
The US Society for Vascular Surgery recommends baseline surveillance with contrast-enhanced CT and color duplex ultrasound in the first month after endovascular aneurysm repair (EVAR).[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
[76]Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 Jan;67(1):2-77.e2.
https://www.jvascsurg.org/article/S0741-5214(17)32369-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/29268916?tool=bestpractice.com
[215]Smith T, Quencer KB. Best practice guidelines: imaging surveillance after endovascular aneurysm repair. AJR Am J Roentgenol. 2020 May;214(5):1165-74.
https://www.doi.org/10.2214/AJR.19.22197
http://www.ncbi.nlm.nih.gov/pubmed/32130043?tool=bestpractice.com
If neither endoleak nor AAA enlargement is documented, imaging should be repeated at 12 months using either contrast-enhanced CT or color duplex ultrasound imaging.[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
[76]Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 Jan;67(1):2-77.e2.
https://www.jvascsurg.org/article/S0741-5214(17)32369-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/29268916?tool=bestpractice.com
Follow-up noncontrast CT imaging is recommended at 5-year intervals after open repair or EVAR.[5]Isselbacher EM, Preventza O, Hamilton Black J 3rd, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Dec 13;146(24):e334-e482.
https://www.doi.org/10.1161/CIR.0000000000001106
http://www.ncbi.nlm.nih.gov/pubmed/36322642?tool=bestpractice.com
[76]Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 Jan;67(1):2-77.e2.
https://www.jvascsurg.org/article/S0741-5214(17)32369-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/29268916?tool=bestpractice.com
The ESVS recommends that all patients should have computed tomography angiography (CTA) within 30 days after the initial repair.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
For patients who have been stratified as low risk of complications (no endoleak, anatomy within manufacturer’s instruction for use [IFU], without high risk features [proximal neck diameter <30 mm and angulation <60 degrees, and iliac diameter <20 mm], adequate overlap, and seal of 10 mm proximal and distal stent graft apposition to arterial wall), the ESVS recommends consideration for limited follow-up, with delayed imaging until 5 years after repair.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
Patients stratified as high risk of complications (presence of T2EL, insufficient overlap or seal <10 mm, anatomy outside IFU, large proximal neck [>30 mm], ectatic iliac fixation zones [>20 mm], or extreme angulation [>60 degrees]) may be considered yearly exams with either CTA or duplex ultrasound.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
CTA is preferred for this purpose and its findings have been shown to have the strongest prognostic importance.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
Duplex ultrasound exam can be used in alternative to verify the absence of endoleaks and assess limb patency and flow, but since it lacks assessment of stent graft overlap, seal length, and kink, it may need to be completed with noncontrast CT.[3]Wanhainen A, Van Herzeele I, Bastos Goncalves F, et al. Editor's choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms. Eur J Vasc Endovasc Surg. 2024 Feb;67(2):192-331.
https://www.ejves.com/article/S1078-5884(23)00889-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38307694?tool=bestpractice.com
Women are at greater risk of postoperative complications (limb ischemia, renal and cardiovascular complications) and mortality (in-hospital and 30-day) than men; strict long-term surveillance is essential in female patients undergoing AAA repair.[163]Liu Y, Yang Y, Zhao J, et al. Systematic review and meta-analysis of sex differences in outcomes after endovascular aneurysm repair for infrarenal abdominal aortic aneurysm. J Vasc Surg. 2020 Jan;71(1):283-296.e4.
https://www.doi.org/10.1016/j.jvs.2019.06.105
http://www.ncbi.nlm.nih.gov/pubmed/31466739?tool=bestpractice.com
Antibiotic prophylaxis of graft infection is required prior to bronchoscopy, gastrointestinal or genitourinary endoscopy, and any dental procedure that may lead to bleeding.[76]Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 Jan;67(1):2-77.e2.
https://www.jvascsurg.org/article/S0741-5214(17)32369-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/29268916?tool=bestpractice.com
Generalized sepsis, groin drainage, pseudoaneurysm formation, or ill-defined pain after open repair or EVAR should prompt evaluation of graft infection.[76]Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 Jan;67(1):2-77.e2.
https://www.jvascsurg.org/article/S0741-5214(17)32369-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/29268916?tool=bestpractice.com
Gastrointestinal bleeding after open repair or EVAR should prompt evaluation of an aorto-enteric fistula.[76]Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 Jan;67(1):2-77.e2.
https://www.jvascsurg.org/article/S0741-5214(17)32369-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/29268916?tool=bestpractice.com