The chronic nature of social anxiety and associated impairments, including risk of substance misuse, should be monitored over the long term in the general practice setting. Effective treatment may require a referral to a psychiatrist and mental health professional trained in cognitive behavioral therapy (CBT) for optimal collaborative care.
Relapse rates can be common after discontinuation of medication. The benefits of CBT tend to last longer than those of pharmacotherapy. Pharmacotherapy should be continued for up to 12 months or longer to prevent relapse (with the exception of benzodiazepines, which are typically only recommended for short-term use).[61]Andrews G, Bell C, Boyce P, et al. Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of panic disorder, social anxiety disorder and generalised anxiety disorder. Aust N Z J Psychiatry. 2018;52(12):1109-72.
https://www.ranzcp.org/files/resources/college_statements/clinician/cpg/anxiety-cpg.aspx
[132]Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. BMJ. 2017 Sep 25;358:j4461.
https://www.bmj.com/content/358/bmj.j4461.long
http://www.ncbi.nlm.nih.gov/pubmed/28947609?tool=bestpractice.com
After this time, the patient and prescriber can discuss whether or not to continue treatment, based on adverse effects and other considerations.[132]Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. BMJ. 2017 Sep 25;358:j4461.
https://www.bmj.com/content/358/bmj.j4461.long
http://www.ncbi.nlm.nih.gov/pubmed/28947609?tool=bestpractice.com
[133]Craske MG, Stein MB. Anxiety. Lancet. 2016 Dec 17;388(10063):3048-59.
http://www.ncbi.nlm.nih.gov/pubmed/27349358?tool=bestpractice.com
If there is agreement to reduce and stop the medication, do so slowly and carefully monitor for the recurrence of symptoms. Consider reviewing additional treatment options, especially CBT, to help prevent relapse following discontinuation of medication.[137]Haug T, Blomhoff S, Hellstrom K, et al. Exposure therapy and sertraline in social phobia: 1-year follow-up of a randomised controlled trial. Br J Psychiatry. 2003 Apr;182:312-8.
https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/exposure-therapy-and-sertraline-in-social-phobia-1year-followup-of-a-randomised-controlled-trial/747376F717429C0723CE8B995B658F2F
http://www.ncbi.nlm.nih.gov/pubmed/12668406?tool=bestpractice.com
In practice, many patients require ongoing, long-term therapy to achieve full benefits and prevent relapse.
For children and young people (ages 6 to 24 years), the International Consortium for Health Outcomes Measurement recommends monitoring symptoms using the Revised Children's Anxiety and Depression Scale (RCADS-25) every 3 months during active treatment and at 1-year follow-up or on transition to another setting.[171]Krause KR, Chung S, Adewuya AO, et al. International consensus on a standard set of outcome measures for child and youth anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder. Lancet Psychiatry. 2021 Jan;8(1):76-86.
http://www.ncbi.nlm.nih.gov/pubmed/33341172?tool=bestpractice.com