Epidemiology

There are differing reports on the prevalence of Dupuytren's contracture depending on region and study design, however worldwide disease prevalence is 8.2%, with the highest rates per continent observed in Africa at 17.2%, and the lowest in America at 2.3%.[4] Other studies report higher prevalence among those of European descent than in other races, and within Europe it is higher in northern than in Mediterranean countries.[5]​ Prevalence in Western countries ranges from 0.6-31.6%.[6]​​ For instance, in the same age group, prevalence has been reported as 22.0% (with progression to contractures in 4.2%), 2.6%, and 0.67% in Dutch, Swedish and UK cohorts respectively.[7][8][9] In Japan, disease prevalence is estimated to be 7.0%.[10]

Dupuytren's disease is twice as common in men as in women, and incidence increases with age.[6][7][8][9][10]

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