Differentials

Congenital scoliosis

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Presents with a clinically evident spinal deformity at a much younger age.[1][2]

INVESTIGATIONS

PA and lateral x-rays: vertebral or rib abnormalities.

Neuromuscular scoliosis

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Spinal deformity presenting in a patient with an underlying neurological or muscular disorder that is usually evident by abnormal developmental history or examination findings.

Neurological examination shows motor weakness, spasticity, or difficulties initiating or controlling motor activity, indicative of upper motor neuron lesions.

Gait assessment reveals abnormalities related to muscle weakness or difficulty with initiation and control of motor activity.

INVESTIGATIONS

Electromyogram and nerve conduction testing: evidence of upper motor neuron lesions.

MRI of brain: to evaluate the aetiology of the abnormalities found on physical examination.

Syringomyelia

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

May present in a very similar manner to adolescent idiopathic scoliosis (AIS).

Earlier onset, with atypical curve patterns and significant curve magnitude at presentation. Subtle neurological abnormalities of asymmetric or hyperreflexive deep tendon reflexes, clonus, a positive Babinski, and abnormal or asymmetric abdominal reflexes.

INVESTIGATIONS

MRI: in patients where there is concern, it is recommended to obtain an MRI of the entire spine to evaluate for an abnormality that may be causing the deformity.

If the abnormality is large enough to be the cause of the patient's presentation/deformity, it should be identifiable on MRI.

Spina bifida

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

In cases where the condition is severe enough to cause spinal deformity, neurological abnormalities such as sensory and motor deficits corresponding to the level of the deformity usually co-exist.

INVESTIGATIONS

Plain films and advanced imaging modalities (e.g., MRI): to reveal incomplete union of the posterior elements of vertebral levels demonstrating various degrees of failure of neural tube closure.

Arnold-Chiari malformation (tethered spinal cord)

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Clinical features range from headaches to identifiable neurological abnormalities such as an abnormal gag reflex and sensory and motor deficits corresponding to the level of the abnormality.

INVESTIGATIONS

MRI of the entire spine: to evaluate for an abnormality that may be causing the deformity, such as a tethered spinal cord or an abnormal position of the hindbrain in relation to the foramen magnum (tonsillar herniation).

Leg-length discrepancy

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Results in the development of a compensatory spinal curvature to balance the trunk over the lower extremities.

Examined in both standing and sitting positions. Assessment on sitting allows the pelvis and spine to balance without the influence of the leg-length discrepancy, thus correcting the observed spinal deformity. This would not occur in the presence of scoliosis.

INVESTIGATIONS

Orthoroentgenogram: to quantify the degree of leg-length discrepancy.

After determination of leg-length discrepancy, repeat standing x-rays with the patient standing on a block to account for the discrepancy demonstrates correction of the postural abnormality.

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