The lifetime prevalence for acute urticaria is approximately 20%.[1]Zuberbier T, Abdul Latiff AH, Abuzakouk M, et al. The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Allergy. 2022 Mar;77(3):734-66.
https://onlinelibrary.wiley.com/doi/10.1111/all.15090
http://www.ncbi.nlm.nih.gov/pubmed/34536239?tool=bestpractice.com
[2]Schaefer P. Acute and chronic urticaria: evaluation and treatment. Am Fam Physician. 2017 Jun 1;95(11):717-24.
https://www.aafp.org/afp/2017/0601/p717.html
http://www.ncbi.nlm.nih.gov/pubmed/28671445?tool=bestpractice.com
While the majority of these cases are acute and self-limiting events, roughly 30% of people will go on to experience prolonged symptoms.[7]Kaplan AP. Urticaria and angioedema. In: Middleton's allergy: principles and practice, vol 2. 6th ed. Philadelphia, PA: Mosby; 2003:1537-1558. Acute urticaria is more common in children and adolescents than in adults, while chronic urticaria more typically affects adults.
The prevalence of chronic urticaria in Spain has been estimated to be 0.6%, and in Germany 1.8%.[8]Gaig P, Olona M, Muñoz Lejarazu D, et al. Epidemiology of urticaria in Spain. J Investig Allergol Clin Immunol. 2004;14:214-220.
http://www.jiaci.org/issues/vol14issue03/214-220.pdf
http://www.ncbi.nlm.nih.gov/pubmed/15552715?tool=bestpractice.com
[9]Zuberbier T, Balke M, Worm M, et al. Epidemiology of urticaria: a representative cross-sectional population survey. Clin Exp Dermatol. 2010 Dec;35(8):869-73.
http://www.ncbi.nlm.nih.gov/pubmed/20456386?tool=bestpractice.com
In chronic urticaria, women are affected more often than men (60% versus 40% of cases, respectively).
Incidence of ACE inhibitor-related angio-oedema has been reported to be more common in black people compared with white people.[10]Mahoney EJ, Devaiah AK. Angioedema and angiotensin-converting enzyme inhibitors: are demographics a risk? Otolaryngol Head Neck Surg. 2008;139:105-108.
http://www.ncbi.nlm.nih.gov/pubmed/18585570?tool=bestpractice.com
Angio-oedema occurs in 0.1% to 0.7% of people taking ACE inhibitors.[11]Kostis WJ, Shetty M, Chowdhury YS, et al. ACE inhibitor-induced angioedema: a review. Curr Hypertens Rep. 2018 Jun 8;20(7):55.
http://www.ncbi.nlm.nih.gov/pubmed/29884969?tool=bestpractice.com
Hereditary angio-oedema affects an estimated 1 in 50,000 people worldwide, and acquired angio-oedema an estimated 1 in 500,000 people.[12]Cicardi M, Aberer W, Banerji A, et al. Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group. Allergy. 2014 May;69(5):602-16.
http://www.ncbi.nlm.nih.gov/pubmed/24673465?tool=bestpractice.com
[13]Cicardi M, Zanichelli A. Acquired angioedema. Allergy Asthma Clin Immunol. 2010 Jul 28;6(1):14.
https://aacijournal.biomedcentral.com/articles/10.1186/1710-1492-6-14
http://www.ncbi.nlm.nih.gov/pubmed/20667117?tool=bestpractice.com