In 2021, the US Centers for Disease Control and Prevention reported that 35% of children aged 4 months to 17 years sleep less than recommended for their age. One large study analysing cross-national data on adolescent sleep found that adolescents meeting the recommended 9 hours sleep/night ranged from 32% to 86% on school days and 79% to 92% on non-school days.[6]Gariepy G, Danna S, Gobiņa I, et al. How are adolescents sleeping? Adolescent sleep patterns and sociodemographic differences in 24 European and North American Countries. J Adolesc Health. 2020 Jun;66(6s):S81-S88.
https://www.jahonline.org/article/S1054-139X(20)30128-2/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/32446613?tool=bestpractice.com
[7]Wheaton AG, Claussen AH. Short sleep duration among infants, children, and adolescents aged 4 months-17 years - United States, 2016-2018. MMWR Morb Mortal Wkly Rep. 2021 Sep 24;70(38):1315-21.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459893
http://www.ncbi.nlm.nih.gov/pubmed/34555000?tool=bestpractice.com
Chronic insomnia disorder affects 10% to 30% of children, and is estimated to be as high as 80% in children with neurodevelopmental disorders such as autism spectrum disorder.[5]American Academy of Sleep Medicine. International Classification of Sleep Disorders – third edition, text revision (ICSD-3-TR). Westchester, IL: American Academy of Sleep Medicine; 2023.[8]Ophoff D, Slaats MA, Boudewyns A, et al. Sleep disorders during childhood: a practical review. Eur J Pediatr. 2018 May;177(5):641-48.
http://www.ncbi.nlm.nih.gov/pubmed/29502303?tool=bestpractice.com
[9]Macias MI, Malhotra S. Behavioral insomnia of childhood. Am J Respir Crit Care Med. 2021 Apr 15;203(8):P20-P21.
https://www.atsjournals.org/doi/epdf/10.1164/rccm.2038P20?role=tab
http://www.ncbi.nlm.nih.gov/pubmed/33856280?tool=bestpractice.com
[10]Maski K, Owens JA. Insomnia, parasomnias, and narcolepsy in children: clinical features, diagnosis, and management. Lancet Neurol. 2016 Oct;15(11):1170-81.
http://www.ncbi.nlm.nih.gov/pubmed/27647645?tool=bestpractice.com
The type of sleep disruption can also vary between age groups; children under 2 years more commonly display sleep-onset difficulties (e.g., needing a parent in the room to fall asleep), while children older than 2 years often display limit-setting behaviours (e.g., stalling bedtime).[9]Macias MI, Malhotra S. Behavioral insomnia of childhood. Am J Respir Crit Care Med. 2021 Apr 15;203(8):P20-P21.
https://www.atsjournals.org/doi/epdf/10.1164/rccm.2038P20?role=tab
http://www.ncbi.nlm.nih.gov/pubmed/33856280?tool=bestpractice.com
Delayed sleep-wake phase disorder (DSWPD) is a circadian rhythm disorder. Of the circadian rhythm disorders, DSWPD is the most common in the paediatric population, with a prevalence of 1% to 16% in adolescents.[5]American Academy of Sleep Medicine. International Classification of Sleep Disorders – third edition, text revision (ICSD-3-TR). Westchester, IL: American Academy of Sleep Medicine; 2023.[11]Sivertsen B, Pallesen S, Stormark KM, et al. Delayed sleep phase syndrome in adolescents: prevalence and correlates in a large population based study. BMC Public Health. 2013 Dec 11;13:1163.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878844
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[12]Gradisar M, Crowley SJ. Delayed sleep phase disorder in youth. Curr Opin Psychiatry. 2013 Nov;26(6):580-5.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142652
http://www.ncbi.nlm.nih.gov/pubmed/24060912?tool=bestpractice.com
Obstructive sleep apnoea (OSA) is present in 1% to 4% of the general paediatric population.[5]American Academy of Sleep Medicine. International Classification of Sleep Disorders – third edition, text revision (ICSD-3-TR). Westchester, IL: American Academy of Sleep Medicine; 2023.[4]Lumeng JC, Chervin RD. Epidemiology of pediatric obstructive sleep apnea. Proc Am Thorac Soc. 2008 Feb 15;5(2):242-52.
http://www.atsjournals.org/doi/full/10.1513/pats.200708-135MG
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[13]Boss EF, Smith DF, Ishman SL. Racial/ethnic and socioeconomic disparities in the diagnosis and treatment of sleep-disordered breathing in children. Int J Pediatr Otorhinolaryngol. 2011 Mar;75(3):299-307.
http://www.ncbi.nlm.nih.gov/pubmed/21295865?tool=bestpractice.com
It is tied to numerous deleterious consequences, including cognitive, developmental, and behavioural impairment; hypertension; poor glucose metabolism; and increased cardiovascular and cerebrovascular disease.[5]American Academy of Sleep Medicine. International Classification of Sleep Disorders – third edition, text revision (ICSD-3-TR). Westchester, IL: American Academy of Sleep Medicine; 2023.[14]Halbower A, Degaonkar M, Barker PB, et al. Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. PLoS Med. 2006 Aug;3(8):e301.
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0030301
http://www.ncbi.nlm.nih.gov/pubmed/16933960?tool=bestpractice.com
[15]Montgomery-Downs HE, Gozal D. Snore-associated sleep fragmentation in infancy: mental development effects and contribution of secondhand cigarette smoke exposure. Pediatrics. 2006 Mar;117(3):e496-502.
http://www.ncbi.nlm.nih.gov/pubmed/16510628?tool=bestpractice.com
[16]Mitchell RB, Kelly J. Behavioral changes in children with mild sleep-disordered breathing or obstructive sleep apnea after adenotonsillectomy. Laryngoscope. 2007 Sep;117(9):1685-8.
http://www.ncbi.nlm.nih.gov/pubmed/17667138?tool=bestpractice.com
[17]Li AM, Au CT, Sung RYT, et al. Ambulatory blood pressure in children with obstructive sleep apnoea - a community based study. Thorax. 2008 Sep;63(9):803-9.
http://www.ncbi.nlm.nih.gov/pubmed/18388205?tool=bestpractice.com
[18]Tamura A, Kawano Y, Watanabe T, et al. Relationship between the severity of obstructive sleep apnea and impaired glucose metabolism in patients with obstructive sleep apnea. Respir Med. 2008 Oct;102(10):1412-6.
http://www.ncbi.nlm.nih.gov/pubmed/18606532?tool=bestpractice.com
[19]Parish J, Somers V. Obstructive sleep apnea and cardiovascular disease. Mayo Clin Proc. 2004 Aug;79(8):1036-46.
http://www.mayoclinicproceedings.org/article/S0025-6196%2811%2962579-2/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/15301332?tool=bestpractice.com
[20]Nishibayashi M, Miyamoto M, Miyamoto T, et al. Correlation between severity of obstructive sleep apnea and prevalence of silent cerebrovascular lesions. J Clin Sleep Med. 2008 Jun 15;4(3):242-7.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546457
http://www.ncbi.nlm.nih.gov/pubmed/18595437?tool=bestpractice.com
The morbidities in children with OSA can sometimes be identified months and years prior to the diagnosis of OSA being made.[21]Jennum P, Ibsen R, Kjellberg J. Morbidity and mortality in children with obstructive sleep apnoea: a controlled national study. Thorax. 2013 Oct;68(10):949-54.
http://thorax.bmj.com/content/68/10/949.long
http://www.ncbi.nlm.nih.gov/pubmed/23749842?tool=bestpractice.com
OSA has a higher prevalence in specific sub-groups of children such as those with craniofacial abnormalities, low muscle tone, Down's syndrome, or obesity.[22]Lee CF, Lee CH, Hsueh WY, et al. Prevalence of obstructive sleep apnea in children with down syndrome: a meta-analysis. J Clin Sleep Med. 2018 May 15;14(5):867-75.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940439
http://www.ncbi.nlm.nih.gov/pubmed/29734982?tool=bestpractice.com
[23]Stebbens VA, Dennis J, Samuels MP, et al. Sleep related upper airway obstruction in a cohort with Down's syndrome. Arch Dis Child. 1991 Nov;66(11):1333-8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1793297
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[24]Marcus CL, Keens TG, Bautista DB, et al. Obstructive sleep apnea in children with Down syndrome. Pediatrics. 1991 Jul;88(1):132-9.
http://www.ncbi.nlm.nih.gov/pubmed/1829151?tool=bestpractice.com
[25]Redline S, Tishler P, Aylor J, et al. Prevalence and risk factors for sleep disordered breathing in children (abstract). Am J Respir Crit Care Med. 1997;155:A843.[26]Landis CE, Redline S. Pediatric sleep apnea: implications of the epidemic of childhood overweight. Am J Respir Crit Care Med. 2007 Mar 1;175(5):436-41.
http://www.atsjournals.org/doi/full/10.1164/rccm.200606-790PP
http://www.ncbi.nlm.nih.gov/pubmed/17158283?tool=bestpractice.com
The peak incidence of OSA in children is between ages 3 and 6 years.[27]Rosen CL. Obstructive sleep apnea syndrome (OSAS) in children: diagnostic challenges. Sleep. 1996 Dec;19(10 Suppl):S274-7.
http://www.ncbi.nlm.nih.gov/pubmed/9085530?tool=bestpractice.com
While snoring is often a prominent symptom of OSA, not all children who snore have OSA. Studies have found that between 3% and 15% of children snore on a regular basis, especially between the ages of 3 and 6 years (13%-35%).[28]Savini S, Ciorba A, Bianchini C, et al. Assessment of obstructive sleep apnoea (OSA) in children: an update. Acta Otorhinolaryngol Ital. 2019 Oct;39(5):289-97.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843580
http://www.ncbi.nlm.nih.gov/pubmed/31708576?tool=bestpractice.com
The only way to definitively distinguish between primary snoring and OSA in a given child is by attended polysomnogram.[29]Chesson AL, Ferber RA, Fry JM, et al. The indications for polysomnography and related procedures. Sleep. 1997 Jun;20(6):423-87.
http://www.ncbi.nlm.nih.gov/pubmed/9302726?tool=bestpractice.com
[30]Marcus CL, Brooks LJ, Draper KA, et al; American Academy of Pediatrics. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics. 2012 Sep;130(3):576-84.
http://pediatrics.aappublications.org/content/130/3/576.long
http://www.ncbi.nlm.nih.gov/pubmed/22926173?tool=bestpractice.com
Nocturnal enuresis, parasomnias, narcolepsy, and restless legs syndrome (RLS) also present in children. Nocturnal enuresis is three times more common in boys than in girls. Prior to 5 years of age it is considered age-appropriate and thus cannot be diagnosed.[31]Thiedke CC. Nocturnal enuresis. Am Fam Physician. 22003 Apr 1;67(7):1499-506.
http://www.ncbi.nlm.nih.gov/pubmed/12722850?tool=bestpractice.com
It is present in 15% to 25% of 5-year-olds, and prevalence is greater in boys.[31]Thiedke CC. Nocturnal enuresis. Am Fam Physician. 22003 Apr 1;67(7):1499-506.
http://www.ncbi.nlm.nih.gov/pubmed/12722850?tool=bestpractice.com
[32]Su MS, Li AM, So HK, et al. Nocturnal enuresis in children: prevalence, correlates, and relationship with obstructive sleep apnea. J Pediatr. 2011 Aug;159(2):238-42.e1.
http://www.ncbi.nlm.nih.gov/pubmed/21397910?tool=bestpractice.com
Primary enuresis denotes children who have never been dry, whereas secondary enuresis occurs in children who have been dry for at least 6 months. OSA is known to be a cause of secondary nocturnal enuresis.[33]Barone JG, Hanson C, DaJusta DG, et al. Nocturnal enuresis and overweight are associated with obstructive sleep apnea. Pediatrics. 2009 Jul;124(1):e53-9.
http://www.ncbi.nlm.nih.gov/pubmed/19564269?tool=bestpractice.com
[34]Ishman SL, Maturo S, Schwartz S, et al. Expert consensus statement: management of pediatric persistent obstructive sleep apnea after adenotonsillectomy. Otolaryngol Head Neck Surg. 2023 Feb;168(2):115-30.
https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1002/ohn.159
http://www.ncbi.nlm.nih.gov/pubmed/36757810?tool=bestpractice.com
The prevalence of narcolepsy ranges from 25 to 50/100,000. The distribution of the age of onset is bimodal, with one peak occurring around the age of 15 years and the other at the age of 35 years.[35]Acquavella J, Mehra R, Bron M, et al. Prevalence of narcolepsy and other sleep disorders and frequency of diagnostic tests from 2013-2016 in insured patients actively seeking care. J Clin Sleep Med. 2020 Aug 15;16(8):1255-63.
https://jcsm.aasm.org/doi/10.5664/jcsm.8482
http://www.ncbi.nlm.nih.gov/pubmed/32807293?tool=bestpractice.com
[36]Lividini A, Pizza F, Filardi M, et al. Narcolepsy type 1 features across the life span: age impact on clinical and polysomnographic phenotype. J Clin Sleep Med. 2021 Jul 1;17(7):1363-70.
https://jcsm.aasm.org/doi/10.5664/jcsm.9198
http://www.ncbi.nlm.nih.gov/pubmed/33666167?tool=bestpractice.com
[37]Longstreth WT Jr, Koepsell TD, Ton TG, et al. The epidemiology of narcolepsy. Sleep. 2007 Jan;30(1):13-26.
http://www.ncbi.nlm.nih.gov/pubmed/17310860?tool=bestpractice.com
[38]Dauvilliers Y, Montplaisir J, Molinari N, et al. Age at onset of narcolepsy in two large populations of patients in France and Quebec. Neurology. 2001 Dec 11;57(11):2029-33.
http://www.ncbi.nlm.nih.gov/pubmed/11739821?tool=bestpractice.com
It often takes between 5 and 10 years from the onset of symptoms until the diagnosis is made.
RLS affects 2% to 4% of school-aged children and adolescents.[39]Picchietti DL, Bruni O, de Weerd A, et al. Pediatric restless legs syndrome diagnostic criteria: an update by the International Restless Legs Syndrome Study Group. Sleep Med. 2013 Dec;14(12):1253-9.
https://www.sciencedirect.com/science/article/pii/S1389945713010708?via%3Dihub
http://www.ncbi.nlm.nih.gov/pubmed/24184054?tool=bestpractice.com
Recent travel across time zones may also affect circadian rhythms, and prevalence varies according to the number of people moving in any given time.
Children with ADHD have higher incidence of sleep disorders, including sleep-disordered breathing, bedtime resistance, night-time awakenings, and daytime sleepiness, than controls.[40]Cortese S, Faraone SV, Konofal E, et al. Sleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studies. J Am Acad Child Adolesc Psychiatry. 2009 Sep;48(9):894-908.
http://www.ncbi.nlm.nih.gov/pubmed/19625983?tool=bestpractice.com
There is also a strong association between paediatric RLS and ADHD.[5]American Academy of Sleep Medicine. International Classification of Sleep Disorders – third edition, text revision (ICSD-3-TR). Westchester, IL: American Academy of Sleep Medicine; 2023.