Evidence
This page contains a snapshot of featured content which highlights evidence addressing key clinical questions including areas of uncertainty. Please see the main topic reference list for details of all sources underpinning this topic.
BMJ Best Practice evidence tables
Evidence tables provide easily navigated layers of evidence in the context of specific clinical questions, using GRADE and a BMJ Best Practice Effectiveness rating. Follow the links at the bottom of the table, which go to the related evidence score in the main topic text, providing additional context for the clinical question. Find out more about our evidence tables.
This table is a summary of the analysis reported in a Cochrane Clinical Answer that focuses on the above important clinical question.
Confidence in the evidence is high or moderate to high where GRADE has been performed and there is no difference in effectiveness between the intervention and comparison for key outcomes.
Population: Sexual partners of women with BV
Intervention: Any antibiotic treatment ᵃ
Comparison: Placebo
| Outcome | Effectiveness (BMJ rating)? | Confidence in evidence (GRADE)? |
|---|---|---|
Recurrence of BV (follow‐up: 1-4 weeks) | No statistically significant difference | Low |
Recurrence of BV (follow‐up: 4-12 weeks) | No statistically significant difference | Very Low |
Clinical improvement during the first week | No statistically significant difference | High |
Clinical improvement (follow‐up: 1-4 weeks) | No statistically significant difference | High |
Clinical improvement (follow‐up: 4-12 weeks) | No statistically significant difference | High |
Symptomatic improvement during the first week | Favours intervention | High |
Symptomatic improvement (follow‐up: 1-4 weeks) | No statistically significant difference | High |
Symptomatic improvement (follow‐up: 4-12 weeks) | No statistically significant difference | High |
Minor adverse events during therapy in sexual partner (follow‐up: 1-12 weeks) | Occurs more commonly with placebo compared with any antibiotic treatment (favours intervention) | Low |
Note ᵃ The included studies used one of the following antibiotics: metronidazole, tinidazole, or clindamycin. See Cochrane Clinical Answer for more information.
This evidence table is related to the following section/s:
Cochrane Clinical Answers
Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.
- Can concurrent antibiotic treatment of sexual partners improve outcomes for women being treated for bacterial vaginosis?
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