Vaginitis is the most common gynaecological diagnosis in the primary care setting.[2]Egan ME, Lipsky MS. Diagnosis of vaginitis. Am Fam Physician. 2000 Sep 1;62(5):1095-104.
http://www.ncbi.nlm.nih.gov/pubmed/10997533?tool=bestpractice.com
Women presenting with vaginal discharge account for approximately 10 million clinic visits each year. In approximately 90% of affected individuals in the US, this condition develops secondary to bacterial vaginosis, candidiasis, or trichomoniasis, of which bacterial vaginosis is the most common.[3]Kent HL. Epidemiology of vaginitis. Am J Obstet Gynecol. 1991 Oct;165(4 Pt 2):1168-76.
http://www.ncbi.nlm.nih.gov/pubmed/1951572?tool=bestpractice.com
Trichomoniasis is the most prevalent non-viral sexually transmitted infection worldwide, affecting an estimated 3.7 million people in the US.[4]Workowski KA, Bachmann LH, Chan PA, et al. Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.
https://www.doi.org/10.15585/mmwr.rr7004a1
http://www.ncbi.nlm.nih.gov/pubmed/34292926?tool=bestpractice.com
[5]World Health Organization. Global incidence and prevalence of selected curable sexually transmitted infections - 2008. Geneva: World Health Organization; 2012.
http://apps.who.int/iris/bitstream/10665/75181/1/9789241503839_eng.pdf?ua=1
The number of cases of vulvovaginal candidiasis in the US is difficult to determine because there is no national surveillance for this infection, but it is estimated that 75% of women will have at least one episode in their lifetime, with 40% to 45% having two or more episodes.[4]Workowski KA, Bachmann LH, Chan PA, et al. Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.
https://www.doi.org/10.15585/mmwr.rr7004a1
http://www.ncbi.nlm.nih.gov/pubmed/34292926?tool=bestpractice.com
Recurrent vulvovaginal candidiasis has an estimated global annual prevalence of 3871 per 100,000 women and is highest in the 25- to 34-year age group (9%).[6]Denning DW, Kneale M, Sobel JD, et al. Global burden of recurrent vulvovaginal candidiasis: a systematic review. Lancet Infect Dis. 2018 Nov;18(11):e339-47.
http://www.ncbi.nlm.nih.gov/pubmed/30078662?tool=bestpractice.com
Black women report higher incidence of candidiasis infections compared with white women.[7]Foxman B, Barlow R, D'Arcy H, et al. Candida vaginitis: self-reported incidence and associated costs. Sex Transm Dis. 2000 Apr;27(4):230-5.
http://www.ncbi.nlm.nih.gov/pubmed/10782746?tool=bestpractice.com
Atrophic vaginitis may affect up to 40% of postmenopausal women, but very few seek medical care.[8]Pandit L, Ouslander JG. Postmenopausal vaginal atrophy and atrophic vaginitis. Am J Med Sci. 1997 Oct;314(4):228-31.
http://www.ncbi.nlm.nih.gov/pubmed/9332260?tool=bestpractice.com
[9]Bachmann GA, Nevadunsky NS. Diagnosis and treatment of atrophic vaginitis. Am Fam Physician. 2000 May 15;61(10):3090-6.
http://www.ncbi.nlm.nih.gov/pubmed/10839558?tool=bestpractice.com