Last reviewed: 16 Mar 2025
Last updated: 06 Dec 2024
Summary
Definition
History and exam
Other diagnostic factors
- >20 weeks' gestation
- absence of symptoms that suggest pre-eclampsia
Risk factors
- nulliparous
- maternal age >35 years
- black or Hispanic ethnicity
- obesity
- mother small for gestational age
- type 1 diabetes mellitus
- migraine
Diagnostic investigations
1st investigations to order
- urinalysis
- FBC
- LFTs
- electrolytes, urea, creatinine
- placental growth factor
Investigations to consider
- uric acid
- 24-hour BP monitoring
- fetal ultrasound
- umbilical artery Doppler velocimetry
- proteinuria (spot testing, 24-hour urine collection)
Treatment algorithm
Contributors
Authors
Aparna Sundaram, DO, MBA, MPH
Board-certified in Preventive Medicine
Board Certified in Lifestyle Medicine
Preventive Medicine Consultants, PLLC
Glendale
AZ
Disclosures
AS declares that she has no competing interests.
Peer reviewers
Caroline Apovian, MD
Associate Professor of Medicine
Boston University School of Medicine
Boston
MA
Disclosures
CA declares that she has no competing interests.
James Walker, MD, FRCP(Glas), FRCP(Edin), FRCOG
Professor of Obstetrics and Gynaecology
St James's University Hospital
Leeds
UK
Disclosures
JW declares that he has no competing interests.
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