Lichen planus (LP) usually develops in middle age between 30 and 60 years and shows a slight female preponderance.[21]Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. J Dtsch Dermatol Ges. 2013 Apr;11(4):309-19.
https://onlinelibrary.wiley.com/doi/10.1111/ddg.12031
http://www.ncbi.nlm.nih.gov/pubmed/23320493?tool=bestpractice.com
[22]Schwager Z, Stern M, Cohen J, et al. Clinical epidemiology and treatment of lichen planus: a retrospective review of 2 tertiary care centers. J Am Acad Dermatol. 2019 Dec;81(6):1397-9.
https://www.jaad.org/article/S0190-9622(19)30616-4/fulltext
In rare circumstances it may arise in childhood.[23]Pandhi D, Singal A, Bhattacharya SN. Lichen planus in childhood: a series of 316 patients. Pediatr Dermatol. 2014 Jan-Feb;31(1):59-67.
http://www.ncbi.nlm.nih.gov/pubmed/23627802?tool=bestpractice.com
[24]Balasubramaniam P, Ogboli M, Moss C. Lichen planus in children: review of 26 cases. Clin Exp Dermatol. 2008 Jul;33(4):457-9.
http://www.ncbi.nlm.nih.gov/pubmed/18355361?tool=bestpractice.com
Prevalence is estimated to be less than 1% worldwide.[21]Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. J Dtsch Dermatol Ges. 2013 Apr;11(4):309-19.
https://onlinelibrary.wiley.com/doi/10.1111/ddg.12031
http://www.ncbi.nlm.nih.gov/pubmed/23320493?tool=bestpractice.com
[25]Schruf E, Biermann MH, Jacob J, et al. Lichen planus in Germany - epidemiology, treatment, and comorbidity. A retrospective claims data analysis. J Dtsch Dermatol Ges. 2022 Aug;20(8):1101-10.
https://onlinelibrary.wiley.com/doi/10.1111/ddg.14808
http://www.ncbi.nlm.nih.gov/pubmed/35913102?tool=bestpractice.com
In India, one study found that LP represents 0.38% of outpatient dermatology diagnoses.[26]Bhattacharya A, Kaur I, Kumar B. Lichen planus: a clinical and epidemiological study. J Dermatol. 2000 Sep;27(9):576-82.
http://www.ncbi.nlm.nih.gov/pubmed/11052233?tool=bestpractice.com
Cutaneous LP is the most common presentation. One retrospective review in the US reported that classic cutaneous LP was the most common sub-type (88%), followed by hypertrophic LP (7%).[22]Schwager Z, Stern M, Cohen J, et al. Clinical epidemiology and treatment of lichen planus: a retrospective review of 2 tertiary care centers. J Am Acad Dermatol. 2019 Dec;81(6):1397-9.
https://www.jaad.org/article/S0190-9622(19)30616-4/fulltext
In India, hypertrophic and actinic cutaneous forms are the most common.[26]Bhattacharya A, Kaur I, Kumar B. Lichen planus: a clinical and epidemiological study. J Dermatol. 2000 Sep;27(9):576-82.
http://www.ncbi.nlm.nih.gov/pubmed/11052233?tool=bestpractice.com
Mucosal involvement is observed in 30% to 70% of patients.[21]Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. J Dtsch Dermatol Ges. 2013 Apr;11(4):309-19.
https://onlinelibrary.wiley.com/doi/10.1111/ddg.12031
http://www.ncbi.nlm.nih.gov/pubmed/23320493?tool=bestpractice.com
The estimated prevalence of oral lichen planus in the general population was 0.89% in one meta-analysis.[27]Li C, Tang X, Zheng X, et al. Global prevalence and incidence estimates of oral lichen planus: a systematic review and meta-analysis. JAMA Dermatol. 2020 Feb 1;156(2):172-81.
https://www.jaad.org/article/S0190-9622(19)30616-4/fulltext
Erosive oral and genital ulceration mostly occurs in women. Concomitant oral involvement is common (occurring in up to 70%) in patients with erosive vulvovaginal LP.[28]American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].
https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2020/07/diagnosis-and-management-of-vulvar-skin-disorders
http://www.ncbi.nlm.nih.gov/pubmed/32590722?tool=bestpractice.com
Nail changes are seen in about 10% to 15% of patients.[29]Gupta MK, Lipner SR. Review of nail lichen planus: epidemiology, pathogenesis, diagnosis, and treatment. Dermatol Clin. 2021 Apr;39(2):221-30.
http://www.ncbi.nlm.nih.gov/pubmed/33745635?tool=bestpractice.com