Case history
Case history
A 70-year-old man presents with generalised fatigue that has slowly progressed over several months. On physical examination, the patient has pale mucous membranes and mild tachycardia. The remainder of the examination is unremarkable.
Other presentations
Patients are often asymptomatic at presentation, and MDS is diagnosed incidentally following routine laboratory tests. If symptoms develop they are usually non-specific and related to anaemia (e.g., weakness, fatigue, decreased exercise tolerance, light-headedness, angina).[4] Less common symptoms are those related to thrombocytopenia (e.g., easy bruising, bleeding) and neutropenia (e.g., infections).[5] Occasionally, MDS can present with autoimmune abnormalities, such as vasculitis, connective tissue disease, and inflammatory arthritis.[6][7][8]
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