Criteria

In order to diagnose POTS in a patient aged 12 years or older, all of the following criteria must be met:[1][2]

  • Sustained increase in heart rate of ≥30 bpm (or ≥40 bpm if aged 12 to 19 years) within 10 minutes of standing from a supine position or head-up tilt[1][4]

  • No orthostatic hypotension (i.e., no sustained drop in systolic blood pressure of ≥20 mmHg)[1]​​[4]

  • Frequent symptoms of orthostatic intolerance during standing, with rapid improvement upon return to a supine position; symptoms may include lightheadedness, palpitations, tremulousness, generalised weakness, blurred vision, and fatigue[1]​​[4]

  • Duration of symptoms for at least 3 months, which interfere with daily living activities[1]​​[4]

  • No other causes for sinus tachycardia identified (e.g., anorexia nervosa, primary anxiety disorders, hyperventilation, anaemia, fever, pain, infection, dehydration, hyperthyroidism, pheochromocytoma, use of cardioactive drugs [e.g., sympathomimetics, anticholinergics], or severe deconditioning caused by prolonged bed rest).[1]

Be aware that POTS remains undefined in patients <12 years old.[1]

Use of this content is subject to our disclaimer