A patient with diabetes mellitus can prevent osteomyelitis by minimising foot trauma and preventing foot ulcers.[20]Lavery LA, Armstrong DG, Wunderlich RP, et al. Risk factors for foot infections in individuals with diabetes. Diabetes Care. 2006 Jun;29(6):1288-93.
http://care.diabetesjournals.org/cgi/content/full/29/6/1288
http://www.ncbi.nlm.nih.gov/pubmed/16732010?tool=bestpractice.com
The patient should be evaluated for ischaemia, with the involvement of multidisciplinary foot teams including podiatrists to improve outcomes.[24]Lipsky BA, Berendt AR, Cornia PB, et al. 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin Infect Dis. 2012 Jun;54(12):e132-73.
https://academic.oup.com/cid/article/54/12/e132/455959
http://www.ncbi.nlm.nih.gov/pubmed/22619242?tool=bestpractice.com
Provide information about appropriate foot care. Recommend that they check, wash, and moisturise their feet daily to avoid breakages in the skin and to detect wounds early. Advise that patients with vascular or neurological foot problems should avoid activities that might cause unnecessary trauma, including walking barefoot or wearing improperly fitted shoes.[25]Calhoun JH, Cantrell J, Cobos J, et al. Treatment of diabetic foot infections: Wagner classification, therapy, and outcome. Foot Ankle. 1988 Dec;9(3):101-6.
http://www.ncbi.nlm.nih.gov/pubmed/3229695?tool=bestpractice.com
For the physician, preventative measures focus on reducing the risks associated with chronic infection.
For the surgeon, debridement, wound irrigation, and muscle-flap or vascularised tissue grafts play major roles in prevention and treatment by removing dead tissue, decreasing bacterial load, and filling dead space with vascularised tissue. Culture-specific antibiotics also play a major role in decreasing the incidence of acute and chronic osteomyelitis. Internal fixation of contaminated dead bone inevitably leads to osteomyelitis and must be avoided.[107]Evans RP, Nelson CL, Harrison BH. The effect of wound environment on the incidence of acute osteomyelitis. Clin Orthop Relat Res. 1993 Jan;(286):289-97.
http://www.ncbi.nlm.nih.gov/pubmed/8425360?tool=bestpractice.com