Patients with unstable angina should be targeted for aggressive lifestyle and risk factor modification.
They may return to their usual activities, but are often advised to avoid strenuous exercise until non-invasive risk stratification (using either exercise or pharmacological stress, and echo or nuclear imaging modalities) is performed in the outpatient setting.
Smoking cessation should be emphasised and aggressive interventions including support groups and pharmacological (nicotine and non-nicotine-containing) products are recommended.[22]Wu AD, Lindson N, Hartmann-Boyce J, et al. Smoking cessation for secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2022 Aug 8;8(8):CD014936.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014936.pub2/full
http://www.ncbi.nlm.nih.gov/pubmed/35938889?tool=bestpractice.com
Similarly, diet and lipid-lowering therapy should be pursued.[146]Hague WE, Simes J, Kirby A, et al. Long-term effectiveness and safety of pravastatin in patients with coronary heart disease: sixteen years of follow-up of the LIPID study. Circulation. 2016 May 10;133(19):1851-60.
http://www.ncbi.nlm.nih.gov/pubmed/27016105?tool=bestpractice.com
Patients should be informed that blood pressure and diabetes management must be tightly controlled as appropriate.
Pharmacotherapy, lifestyle changes, and cardiac rehabilitation are well demonstrated to be beneficial and together are additive in reducing mortality.[1]Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC guidelines for the management of acute coronary syndromes. Eur Heart J. 2023 Oct 12;44(38):3720-826.
https://academic.oup.com/eurheartj/article/44/38/3720/7243210
http://www.ncbi.nlm.nih.gov/pubmed/37622654?tool=bestpractice.com
[147]Beleigoli A, Foote J, Gebremichael LG, et al. Clinical effectiveness and utilisation of cardiac rehabilitation after hospital discharge: data linkage analysis of 84,064 eligible discharged patients (2016-2021). Heart Lung Circ. 2024 Jul;33(7):1036-45.
https://www.heartlungcirc.org/article/S1443-9506(24)00048-9/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38443278?tool=bestpractice.com
[148]Dibben G, Faulkner J, Oldridge N, et al. Exercise-based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev. 2021 Nov 6;11(11):CD001800.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001800.pub4/full
http://www.ncbi.nlm.nih.gov/pubmed/34741536?tool=bestpractice.com