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Last reviewed: 9 Mar 2025
Last updated: 27 Mar 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • palpable pulsatile abdominal mass

Other diagnostic factors

  • abdominal, flank, or back pain
  • hypotension
  • loss of consciousness
  • pallor
  • abdominal distension
  • fever

Risk factors

  • cigarette smoking
  • hereditary/family history
  • increased age
  • male sex (prevalence)
  • female sex (rupture)
  • congenital/connective tissue disorders
  • hyperlipidaemia
  • COPD
  • atherosclerosis (i.e., coronary artery disease [CAD], peripheral arterial occlusive disease)
  • hypertension
  • central obesity
  • non-diabetic
  • fluoroquinolone antibiotics
  • aneurysms elsewhere in the body

Diagnostic investigations

Investigations to consider

  • computed tomography angiography (CTA)
  • cross match
  • clotting screen
  • erythrocyte sedimentation rate (ESR)/C-reactive protein (CRP)
  • FBC
  • blood cultures
  • positron emission tomography-computed tomography (PET-CT)

Treatment algorithm

Contributors

Expert advisers

Greg McMahon, MD, FRCS

Consultant Vascular Surgeon

University Hospitals of Leicester NHS Trust

Honorary Lecturer, College of Life Sciences

University of Leicester

Leicester

UK

Disclosures

GM has received honoraria from Gore Medical and Terumo Aortic, manufacturers of abdominal aortic aneurysm stent grafts, for educational and training activities.

Acknowledgements

BMJ Best Practice would like to gratefully acknowledge the previous expert contributors, whose work has been retained in parts of the content:

Matt J. Bown MB BCh, MD, FRCS, PGCert (Bioinformatics)

Professor of Vascular Surgery

Department of Cardiovascular Sciences

University of Leicester, Leicester Royal Infirmary

Leicester

UK

Andrew Duncan MBBS, BSc, MRCS

Honorary Research Fellow

Department of Cardiovascular Sciences

University of Leicester

Leicester

UK

Disclosures

MJB has grant funding from the British Heart Foundation and the National Institute for Health Research. AD declares that he has no competing interests.

Peer reviewers

Ian Chetter, MBChb, FRCS (eng), MD, FRCS (Gen surg), PGCert Medical Ultrasound, PGDip Clinical Education

Chair of Surgery

University of Hull

Honorary Consultant Vascular Surgeon

Hull University Teaching Hospitals NHS Trust

Hull

UK

Disclosures

IC declares he has no competing interests

Editors

Annabel Sidwell

Section Editor, BMJ Best Practice

Disclosures

AS declares that she has no competing interests.

Rachel Wheeler

Lead Section Editor, BMJ Best Practice

Disclosures

RW declares that she has no competing interests.

Adam Mitchell

Drug Editor, BMJ Best Practice

Disclosures

AM declares that he has no competing interests.

Julie Costello

Comorbidities Editor, BMJ Best Practice

Disclosures

JC declares that she has no competing interests.

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