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4

Myocarditis

Apical 4-chamber echocardiogram in a patient presenting with myocarditis showing a slightly dilated left ventricle with spontaneous ultrasonic contrast indicating severely impaired left ventricular systolic function

From: Rasmussen TB, Dalager S, Andersen NH, et al. BMJ Case Reports 2009; doi:10.1136/bcr.09.2008.0997

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1

Myocarditis

Histological findings in a patient with giant cell myocarditis. A: severe myocardial necrosis and fibrotic replacement of the cardiomyocytes with granulation tissue and fibrosis is present in a section from the anterolateral left ventricular wall; B: a sharp demarcating border between vital and necrotic myocardium is seen, confirmed by additional immunohistochemical staining for myoglobin; C: at the inflammatory border, cells consisting of prominent multi-nucleated giant cells, macrophages, lymphocytes, and eosinophilic granulocytes are seen in close proximity to vital myocardium; D: immunohistochemical staining for complement 4d is positive in all vessels, suggestive of complement cascade activation

From: Rasmussen TB, Dalager S, Andersen NH, et al. BMJ Case Reports 2009; doi:10.1136/bcr.09.2008.0997

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2

Myocarditis

Autopsy findings in a patient with myocarditis. The explanted heart (A and B) is enlarged and thinned with dilatation mainly of the right ventricle. The right atrium is moderately dilated and the left atrium is not enlarged (B)

From: Rasmussen TB, Dalager S, Andersen NH, et al. BMJ Case Reports 2009; doi:10.1136/bcr.09.2008.0997

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3

Myocarditis

Apical 4-chamber transthoracic echocardiogram in a patient with myocarditis. The right ventricle is dilated with hypokinesis. Triscupid regurgitation is present with a reduced continuous wave Doppler gradient indicating right ventricular failure

From: Rasmussen TB, Dalager S, Andersen NH, et al. BMJ Case Reports 2009; doi:10.1136/bcr.09.2008.0997

See this image in context in the following section/s:

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