Epidemiological data have shown a high prevalence of erectile dysfunction (ED) worldwide, but estimations are difficult due to the range of definitions and screening tests for ED used.[5]Kessler A, Sollie S, Challacombe B, et al. The global prevalence of erectile dysfunction: a review. BJU Int. 2019 Oct;124(4):587-99.
http://www.ncbi.nlm.nih.gov/pubmed/31267639?tool=bestpractice.com
The prevalence of ED in Germany has been estimated at 19.2% among 30- to 80-year-old men in Cologne.[6]Braun M, Wassmer G, Klotz T, et al. Epidemiology of erectile dysfunction: results of the 'Cologne Male Survey'. Int J Impot Res. 2000 Dec;12(6):305-11.
https://www.researchgate.net/publication/11923119_Epidemiology_of_erectile_dysfunction_Results_of_the_'Cologne_Male_Survey'
http://www.ncbi.nlm.nih.gov/pubmed/11416833?tool=bestpractice.com
The incidence of new cases is also high. In Brazil, over a 2-year period, it has been estimated that there are 65.6 cases per 1000 men annually.[7]Moreira ED Jr, Lbo CF, Diament A, et al. Incidence of erectile dysfunction in men 40 to 69 years old: results from a population-based cohort study in Brazil. Urology. 2003 Feb;61(2):431-6.
http://www.ncbi.nlm.nih.gov/pubmed/12597962?tool=bestpractice.com
In one study in the Netherlands the incidence of significant ED over a period of 4.2 years has been estimated at 19.2 cases per 1000 men annually.[8]Schouten BW, Bosch JL, Bernsen RM, et al. Incidence rates of erectile dysfunction in the Dutch general population. Effects of definition, clinical relevance and duration of follow-up in the Krimpen Study. Int J Impot Res. 2005 Jan-Feb;17(1):58-62.
http://www.nature.com/ijir/journal/v17/n1/full/3901264a.html
http://www.ncbi.nlm.nih.gov/pubmed/15510192?tool=bestpractice.com
In the US, some degree of erectile difficulty is reported by half of men aged 40 to 70 years with an incidence rate of around 26 cases per 1000 man-years.[9]Feldman HA, Goldstein I, Hatzichristou DG, et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol. 1994 Jan;151(1):54-61.
http://www.ncbi.nlm.nih.gov/pubmed/8254833?tool=bestpractice.com
[10]Johannes CB, Araujo AB, Feldman HA, et al. Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts male aging study. J Urol. 2000 Feb;163(2):460-3.
http://www.ncbi.nlm.nih.gov/pubmed/10647654?tool=bestpractice.com
The incidence and prevalence rates of ED increases with age.[5]Kessler A, Sollie S, Challacombe B, et al. The global prevalence of erectile dysfunction: a review. BJU Int. 2019 Oct;124(4):587-99.
http://www.ncbi.nlm.nih.gov/pubmed/31267639?tool=bestpractice.com
However, one study showed that one in four patients seeking first medical help for new onset ED was younger than 40 years.[11]Capogrosso P, Colicchia M, Ventimiglia E, et al. One patient out of four with newly diagnosed erectile dysfunction is a young man - worrisome picture from the everyday clinical practice. J Sex Med. 2013 Jul;10(7):1833-41.
http://www.ncbi.nlm.nih.gov/pubmed/23651423?tool=bestpractice.com
In one study of young (18 to 31 years) sexually active men, mild erectile dysfunction reported in 11.3% and 2.9% reported moderate-to-severe erectile dysfunction.[12]Calzo JP, Austin SB, Charlton BM, et al. Erectile dysfunction in a sample of sexually active young adult men from a U.S. cohort: demographic, metabolic and mental health correlates. J Urol. 2021 Feb;205(2):539-44.
http://www.ncbi.nlm.nih.gov/pubmed/32935616?tool=bestpractice.com
Race variation has been observed, in that Hispanic men were nearly twice as likely to have ED and develop the condition at younger ages.[13]Saigal CS, Wessells H, Pace J, et al. Predictors and prevalence of erectile dysfunction in a racially diverse population. Arch Intern Med. 2006 Jan 23;166(2):207-12.
http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/409619
http://www.ncbi.nlm.nih.gov/pubmed/16432090?tool=bestpractice.com
However, this finding is not consistently supported.[14]Kupelian V, Link CL, Rosen RC, et al. Socioeconomic status, not race/ethnicity, contributes to variation in the prevalence of erectile dysfunction: results from the Boston Area Community Health (BACH) Survey. J Sex Med. 2008 Jun;5(6):1325-33.
http://www.ncbi.nlm.nih.gov/pubmed/18410305?tool=bestpractice.com