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Last reviewed: 14 Mar 2025
Last updated: 09 May 2022

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • diarrhoea
  • vomiting
  • nausea
  • abdominal pain

Other diagnostic factors

  • malaise
  • anorexia
  • fever
  • volume depletion

Risk factors

  • exposure to contaminated food or water sources
  • close contact with infected people
  • poor hygiene
  • extreme ages
  • HIV infection
  • organ transplantation
  • chronic illness

Diagnostic investigations

1st investigations to order

  • clinical diagnosis
  • full blood count
  • urea and electrolytes
  • creatinine

Investigations to consider

  • stool for culture, ova, and parasites
  • stool viral culture

Treatment algorithm

Contributors

Expert advisers

Alexander Alexiou, MB, BS, BSc, DCH, FRCEM, DipIMC RSEd

Consultant in Emergency Medicine

Royal London Hospital

Consultant in Physician Response Unit

Barts Health NHS Trust/London Air Ambulance

London

UK

Disclosures

AA declares that he has no competing interests.

Acknowledgements

BMJ Best Practice would like to gratefully acknowledge the previous expert contributors, whose work has been retained in parts of the content:

Kyle E. Brown MD, FAASLD

Associate Professor of Internal Medicine

University of Iowa

Carver College of Medicine

Iowa City

IA

Jenny Currigan

ST6 Emergency Medicine Trainee

Royal London Hospital

Barts Health NHS Trust

London

UK

Johann Grundlingh MBChB, FCEM, FFICM, EDICM, DFMS, DipMedTox, MMedTox, MSB, ERT, MEWI, MBA

Emergency Medicine Consultant

Royal London Hospital

Barts Health NHS Trust

London

Honorary Senior Lecturer

Queen Mary University

London

UK

Disclosures

KEB, JC and JG declare that they have no competing interests.

Peer reviewers

Adam Evans

Consultant Physician

Acute Medicine and Infectious Diseases Physician

Royal Victoria Infirmary

Newcastle upon Tyne

UK

Disclosures

AE declares that he has no competing interests.

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