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Last reviewed: 16 Mar 2025
Last updated: 17 Jul 2024

Summary

Definition

History and exam

Key diagnostic factors

  • vaginal bleeding
  • abdominal pain
  • uterine contractions
  • uterine tenderness

Other diagnostic factors

  • lower back pain
  • fetal death

Risk factors

  • chronic hypertension
  • pre-eclampsia
  • smoking
  • cocaine use
  • trauma
  • prior caesarean delivery
  • preterm premature rupture of the membranes
  • multiparity
  • advanced maternal age
  • polyhydramnios
  • chorioamnionitis
  • uterine malformations
  • prior placental abruption
  • multi-fetal gestations
  • oligohydramnios
  • uterine leiomyomas
  • thrombophilias

Diagnostic investigations

1st investigations to order

  • fetal monitoring
  • Hb and haematocrit
  • coagulation studies
  • Kleihauer-Betke (K-B) test
  • ultrasound

Treatment algorithm

Contributors

Authors

Yinka Oyelese, MD, FACOG
Yinka Oyelese

Director, Obstetric Imaging

Beth Israel Deaconess Medical Center

Harvard Medical School

Boston

MA

Disclosures

YO is an author of a number of references cited in this topic.

Anthony M. Vintzileos, MD, FACOG
Anthony M. Vintzileos

Chairman

Department of Obstetrics and Gynecology

Winthrop University Hospital

Mineola

Professor

Obstetrics, Gynecology, and Reproductive Medicine

Stony Brook School of Medicine

Stony Brook

NY

Disclosures

AMV declares that he has no competing interests.

Peer reviewers

Christopher Glantz, MD, MPH

Professor of Obstetrics and Gynecology

University of Rochester School of Medicine

Rochester

New York

NY

Disclosures

CG declares that he has no competing interests.

Austin Ugwumadu, PhD, FRCOG

Consultant/Senior Lecturer in Obstetrics and Gynaecology

St George's Hospital

London

UK

Disclosures

AU declares that he has no competing interests.

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