Lifetime prevalence of cluster headache is reported as 0.12%, although data are limited and estimates vary.[1]Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ. 2022 Mar 16;376:e059577.
http://www.ncbi.nlm.nih.gov/pubmed/35296510?tool=bestpractice.com
[5]Wei DY, Yuan Ong JJ, Goadsby PJ. Cluster headache: epidemiology, pathophysiology, clinical features, and diagnosis. Ann Indian Acad Neurol. 2018 Apr;21(suppl 1):S3-S8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909131
http://www.ncbi.nlm.nih.gov/pubmed/29720812?tool=bestpractice.com
Approximately 80% of affected people have the episodic form of cluster headache and 20% have the chronic form; episodic cluster headache can change to the chronic form and vice versa.[1]Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ. 2022 Mar 16;376:e059577.
http://www.ncbi.nlm.nih.gov/pubmed/35296510?tool=bestpractice.com
[5]Wei DY, Yuan Ong JJ, Goadsby PJ. Cluster headache: epidemiology, pathophysiology, clinical features, and diagnosis. Ann Indian Acad Neurol. 2018 Apr;21(suppl 1):S3-S8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909131
http://www.ncbi.nlm.nih.gov/pubmed/29720812?tool=bestpractice.com
This is one of the few primary headaches that affects men predominantly. The male-to-female ratio is reported to be approximately 2.5:1; this has fallen in more recent studies, possibly due to fewer misdiagnoses in women.[1]Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ. 2022 Mar 16;376:e059577.
http://www.ncbi.nlm.nih.gov/pubmed/35296510?tool=bestpractice.com
[5]Wei DY, Yuan Ong JJ, Goadsby PJ. Cluster headache: epidemiology, pathophysiology, clinical features, and diagnosis. Ann Indian Acad Neurol. 2018 Apr;21(suppl 1):S3-S8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909131
http://www.ncbi.nlm.nih.gov/pubmed/29720812?tool=bestpractice.com
Data about any racial and ethnic differences in cluster headache are limited. One review suggested that there is a greater male predominance, lower prevalence of chronic cluster headache, less restlessness, and less circadian periodicity in Asian people, compared with European and North American populations.[6]Peng KP, Takizawa T, Lee MJ. Cluster headache in Asian populations: similarities, disparities, and a narrative review of the mechanisms of the chronic subtype. Cephalalgia. 2020 Sep;40(10):1104-12.
https://www.doi.org/10.1177/0333102420923646
http://www.ncbi.nlm.nih.gov/pubmed/32397739?tool=bestpractice.com
Onset of cluster headache can occur at any age, but is usually between 20 and 40 years.[1]Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ. 2022 Mar 16;376:e059577.
http://www.ncbi.nlm.nih.gov/pubmed/35296510?tool=bestpractice.com
Although extremely rare, it has been reported in children as young as 2 years.[7]Bastos SNMAN, Barbosa BLF, Silva SF, et al. Cluster headache in children and adolescents: a systematic review of case reports. Dev Med Child Neurol. 2021 Oct;63(10):1155-60.
https://onlinelibrary.wiley.com/doi/10.1111/dmcn.14923
http://www.ncbi.nlm.nih.gov/pubmed/33987834?tool=bestpractice.com