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Images
Retinoblastoma
Histopathology of retinoblastoma. This image demonstrates the classical features of retinoblastoma, including densely packed, small, round tumor cells with hyperchromatic nuclei and scant cytoplasm, arranged in sheets. The absence of Flexner-Wintersteiner rosettes in this specimen does not preclude the diagnosis, as their presence is not obligatory. These histopathological features are typical of this aggressive retinal tumor and provide critical information for diagnosis, staging, and prognosis
PR J. L. Kemeny, ISM/Science Photo Library; used with permission
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Retinoblastoma
Macular retinoblastoma in the right eye
Personal collection of Dr Timothy Murray
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Retinoblastoma
Vitreous seeding associated with retinoblastoma
Personal collection of Dr Timothy Murray
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Retinoblastoma
Two large retinoblastoma foci in the left eye; note the associated subretinal seeding
Personal collection of Dr Timothy Murray
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Retinoblastoma
MRI pattern of retinoblastoma with optic nerve involvement (sagittal enhanced T1-weighted sequence)
Aerts I, et al. Orphanet J Rare Dis 2006 Aug 25; 1: 31; licensed under CC BY 2.0
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Retinoblastoma
Aspect of trilateral retinoblastoma (MRI)
Aerts I, et al. Orphanet J Rare Dis 2006 Aug 25; 1: 31; licensed under CC BY 2.0
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Retinoblastoma
Leukocoria (white pupillary light reflex) in the left eye of a patient with unilateral retinoblastoma
Personal collection of Dr Timothy Murray
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Retinoblastoma
Large retinoblastoma focus in the left eye
Personal collection of Dr Timothy Murray
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Retinoblastoma
Light micrograph of a retinal section from a patient with retinoblastoma, a rare form of intraocular cancer. The tumor shows disrupted retinal architecture and infiltrative growth of atypical cells. Immunohistochemistry with anti-rhodopsin antibodies highlights areas of preserved photoreceptor differentiation within the retinal tissue. This staining aids in identifying residual retinal layers amidst the malignant cellular proliferation
PR J. L. Kemeny, ISM/Science Photo Library; used with permission
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Retinoblastoma
Ultrasound of retinoblastoma
Aerts I, et al. Orphanet J Rare Dis 2006 Aug 25; 1: 31; licensed under CC BY 2.0
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