Criteria

Assessing risk of adverse outcome and treatment failure[2]

It is important to determine the severity of the IAA infection and stratify the patient's risk at diagnosis, as this influences treatment.

  • Assess phenotypic and physiologic factors:

    • Signs of sepsis

    • Extremes of age

    • Comorbidities

    • Extent of abdominal infection and adequacy of source control

    • Presence of resistant or opportunistic pathogen.

  • Characterize patients as either low or high risk for treatment failure or mortality.

  • Assess for community-acquired or health care-acquired infection.

  • Patients with Surviving Sepsis Campaign criteria for sepsis or septic shock, and those with APACHE II score greater than or equal to 10, are at higher risk.

  • Prolonged length of hospitalization prior to surgery for intra-abdominal infection.

  • Patients with diffuse peritonitis.

  • Patients with delayed source control.

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