Case history

Case history #1

A 42-year-old man presents with a recent history of abdominal pain, distension, and nausea. Urea breath testing for Helicobacter pylori is positive.

Case history #2

A 58-year-old white woman of North European descent presents with a 2-month history of increasing fatigue, difficulty with ambulation, and memory deficits. Family history is notable for autoimmune disease. Laboratory evaluation is remarkable for a macrocytic anemia, a markedly reduced serum vitamin B₁₂, and presence of antiparietal cell antibodies.

Other presentations

Erosive gastritis may occur in response to nonsteroidal anti-inflammatory drugs (NSAIDs), or alcohol use or misuse, and to bile reflux into the stomach following previous gastric surgery or biliary surgery, including cholecystectomy.[1][2][3][5][6][7][8] Stress gastritis (most commonly related to mucosal ischemia) may develop in critically ill patients, generally in the intensive care unit population.[9] Autoimmune gastritis occurs when antiparietal cell antibodies stimulate a chronic inflammatory, mononuclear, and lymphocytic infiltrate involving the oxyntic mucosa, leading to the loss of parietal and chief cells in the gastric corpus.[3][10] Phlegmonous gastritis is a rare but life-threatening infection of the gastric submucosa and muscularis propria seen in immunocompromised patients.[11][12][13][14]

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