Evidence
This page contains a snapshot of featured content which highlights evidence addressing key clinical questions including areas of uncertainty. Please see the main topic reference list for details of all sources underpinning this topic.
BMJ Best Practice evidence tables
Evidence tables provide easily navigated layers of evidence in the context of specific clinical questions, using GRADE and a BMJ Best Practice Effectiveness rating. Follow the links at the bottom of the table, which go to the related evidence score in the main topic text, providing additional context for the clinical question. Find out more about our evidence tables.
This table is a summary of the analysis reported in a Cochrane Clinical Answer that focuses on the above important clinical question.
Confidence in the evidence is moderate or low to moderate where GRADE has been performed and the intervention may be more effective/beneficial than the comparison for key outcomes.
Population: Children and adults with or without soil-transmitted infections (all settings with STH infection)
Intervention: WASH
Comparison: Control (regular government health education curriculum, initial health education, posters in some studies, or no intervention)
| Outcome | Effectiveness (BMJ rating)? | Confidence in evidence (GRADE)? |
|---|---|---|
Any STH prevalence (follow‐up: 7-48 months): RCTs | No statistically significant difference ᵃ | Moderate |
Any STH prevalence (follow‐up: 7-48 months): non-RCTs | Favors intervention | Low |
Any adverse events | - | None of the studies identified by the review assessed this comparison |
Note ᵃ The Cochrane Clinical Answer (CCA) noted that fewer people receiving WASH had any STH infection, ascaris lumbricoides, or hookworm (27 versus 30, 16 versus 18, and 5 versus 6 per 100 participants, respectively; results on average) but the results did not reach statistical significance.
This evidence table is related to the following section/s:
Cochrane Clinical Answers
Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.
- What are the effects of interventions to improve water, sanitation, and hygiene (WASH) for preventing soil‐transmitted helminth infection?
- How do different praziquantel dosing regimens compare for the treatment of urinary schistosomiasis?
- How does 40 mg praziquantel compare with placebo and other drugs for treating urinary schistosomiasis?
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