Evaluation of maculopapular rash

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Evaluation of maculopapular rash

Acute graft-versus-host disease of the skin (grade I)

Courtesy of Dr John Levine, Professor, Blood and Marrow Transplantation Program, University of MIchigan; used with permission

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• Etiology

Evaluation of maculopapular rash

Koplik spots

Centers for Disease Control and Prevention

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Evaluation of maculopapular rash

Toxic epidermal necrolysis with epidermal loss, ocular involvement, and ecthyma gangrenosum

From the personal collection of Dr A. Kowal-Vern

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Evaluation of maculopapular rash

Koplik spots

Centers for Disease Control and Prevention

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• Etiology

Evaluation of maculopapular rash

Erythema multiforme with target lesions

Courtesy of the CDC Public Health Image Library

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Evaluation of maculopapular rash

Hypersensitivity rash due to penicillin

CDC Public Health Image Library

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• Diagnosis Approach

Evaluation of maculopapular rash

Erythema multiforme with perioral ulceration

Courtesy of the CDC Public Health Image Library

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Evaluation of maculopapular rash

Stevens-Johnson Syndrome: epidermal loss on soles of feet

From the personal collection of Dr A. Kowal-Vern

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Evaluation of maculopapular rash

Erythema infectiosum (Fifth disease) in a 10-year-old girl

From the personal teaching collection of Hobart W. Walling

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Evaluation of maculopapular rash

Viral exanthem presenting as a maculopapular eruption. Note urticarial appearance of nonscaling erythematous macules and papules on the trunk of this older child

Photograph courtesy of Hobart W. Walling

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Evaluation of maculopapular rash

During a punch biopsy, local anesthetic is instilled by injection into the surrounding skin. With the skin stretched perpendicular to normal relaxation lines, a disposable skin biopsy punch with a round stainless steel blade (at least 3 mm or 4 mm in diameter is recommended) is applied perpendicular to the skin. Pressure is applied with a rotating action until a "give" is felt as the blade pierces through the subcutaneous tissue. The cylindrical core of tissue is removed and placed in a labeled sample pot containing a suitable fixative solution

Created by the BMJ Knowledge Centre

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Evaluation of maculopapular rash

Characteristic spotted rash of Rocky Mountain spotted fever

Courtesy of the CDC Public Health Image Library

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• Urgent considerations
• Diagnosis Approach

Evaluation of maculopapular rash

Stevens-Johnson Syndrome: targetoid lesions and epidermal loss

From the personal collection of Dr A. Kowal-Vern

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Evaluation of maculopapular rash

Scarlet fever rash on the forearm due to group A Streptococcus bacteria

Courtesy of the CDC Public Health Image Library

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Evaluation of maculopapular rash

Syphilis presenting with a generalized rash

Courtesy of the CDC Public Health Image Library

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Evaluation of maculopapular rash

Morbilliform rash (resembling measles) resulting from toxic shock syndrome

Courtesy of the CDC Public Health Image Library

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Evaluation of maculopapular rash

Viral exanthem presenting as a maculopapular eruption. Note the erythematous papules are larger than macules on the leg of a young adult

Photograph courtesy of Hobart W. Walling

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Evaluation of maculopapular rash

Drug eruption due to phenytoin

Photograph courtesy of Brian L. Swick

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Evaluation of maculopapular rash

Rubella presenting as a generalized abdominal rash

Courtesy of the CDC Public Health Image Library

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• Etiology

Videos

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  Venepuncture and phlebotomy: animated demonstration

  How to take a venous blood sample from the antecubital fossa using a vacuum needle.