The treatment of inguinal hernia in adults remains largely surgical as this offers the only potential for cure. Surgery is also important for preventing strangulation of hernias, and for treating hernias that are painful and difficult to reduce.
Watchful waiting is a reasonable option in adults with minimally symptomatic or asymptomatic inguinal hernia, especially if they are frail, elderly, or high risk for any kind of surgical procedure.
Watchful waiting
Whether all hernias should be repaired or not is controversial. Watchful waiting is considered a safe strategy in adults with minimally symptomatic or asymptomatic inguinal hernia, and this is reflected in guideline recommendations.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[25]van Veenendaal N, Simons M, Hope W, et al. Consensus on international guidelines for management of groin hernias. Surg Endosc. 2020 Jun;34(6):2359-77.
https://www.doi.org/10.1007/s00464-020-07516-5
http://www.ncbi.nlm.nih.gov/pubmed/32253559?tool=bestpractice.com
[54]Fitzgibbons RJ Jr, Giobbie-Hurder A, Gibbs JO, et al. Watchful waiting vs repair of inguinal hernia in minimally symptomatic men: a randomized clinical trial. JAMA. 2006 Jan 18;295(3):285-92.
http://jama.ama-assn.org/content/295/3/285.long
http://www.ncbi.nlm.nih.gov/pubmed/16418463?tool=bestpractice.com
Over time, many patients with initially asymptomatic hernias will develop symptoms and undergo elective repair.[9]Itani KMF, Fitzgibbons R. Approach to groin hernias. JAMA Surg. 2019 Jun 1;154(6):551-2.
https://www.doi.org/10.1001/jamasurg.2018.5564
http://www.ncbi.nlm.nih.gov/pubmed/30865244?tool=bestpractice.com
[54]Fitzgibbons RJ Jr, Giobbie-Hurder A, Gibbs JO, et al. Watchful waiting vs repair of inguinal hernia in minimally symptomatic men: a randomized clinical trial. JAMA. 2006 Jan 18;295(3):285-92.
http://jama.ama-assn.org/content/295/3/285.long
http://www.ncbi.nlm.nih.gov/pubmed/16418463?tool=bestpractice.com
[55]Mizrahi H, Parker MC. Management of asymptomatic inguinal hernia: a systematic review of the evidence. Arch Surg. 2012 Mar;147(3):277-81.
http://www.ncbi.nlm.nih.gov/pubmed/22430913?tool=bestpractice.com
[56]Fitzgibbons RJ Jr, Ramanan B, Arya S, et al. Long-term results of a randomized controlled trial of a nonoperative strategy (watchful waiting) for men with minimally symptomatic inguinal hernias. Ann Surg. 2013 Sep;258(3):508-15.
http://www.ncbi.nlm.nih.gov/pubmed/24022443?tool=bestpractice.com
[57]Chung L, Norrie J, O'Dwyer PJ. Long-term follow-up of patients with a painless inguinal hernia from a randomized clinical trial. Br J Surg. 2011 Apr;98(4):596-9.
http://www.ncbi.nlm.nih.gov/pubmed/21656724?tool=bestpractice.com
[58]O'Dwyer PJ, Norrie J, Alani A, et al. Observation or operation for patients with an asymptomatic inguinal hernia: a randomized clinical trial. Ann Surg. 2006 Aug;244(2):167-73.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602168
http://www.ncbi.nlm.nih.gov/pubmed/16858177?tool=bestpractice.com
A study of 720 men (≥18 years of age) with minimally symptomatic or asymptomatic inguinal hernia found that 23% who were randomly assigned to watchful waiting crossed over to surgery at 2 years due to the development of symptoms, usually discomfort.[54]Fitzgibbons RJ Jr, Giobbie-Hurder A, Gibbs JO, et al. Watchful waiting vs repair of inguinal hernia in minimally symptomatic men: a randomized clinical trial. JAMA. 2006 Jan 18;295(3):285-92.
http://jama.ama-assn.org/content/295/3/285.long
http://www.ncbi.nlm.nih.gov/pubmed/16418463?tool=bestpractice.com
Incarceration developed in 2 patients assigned to watchful waiting. By 7.5 years post-randomization, 72% of the watchful waiting group (46% follow-up) had undergone operative repair.[56]Fitzgibbons RJ Jr, Ramanan B, Arya S, et al. Long-term results of a randomized controlled trial of a nonoperative strategy (watchful waiting) for men with minimally symptomatic inguinal hernias. Ann Surg. 2013 Sep;258(3):508-15.
http://www.ncbi.nlm.nih.gov/pubmed/24022443?tool=bestpractice.com
One UK study of 160 older men (≥55 years of age) randomly assigned to surgery or watchful waiting found that 29% had crossed over from watchful waiting to surgery after 1 year.[58]O'Dwyer PJ, Norrie J, Alani A, et al. Observation or operation for patients with an asymptomatic inguinal hernia: a randomized clinical trial. Ann Surg. 2006 Aug;244(2):167-73.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602168
http://www.ncbi.nlm.nih.gov/pubmed/16858177?tool=bestpractice.com
There were 3 serious hernia-related adverse events in those who crossed over, and one of these resulted in death (postoperative myocardial infarction) following significant deterioration of comorbid cardiovascular disease during observation. At 10 years post-randomization (71% follow-up), 68% of the watchful waiting group had crossed over to surgical repair.[57]Chung L, Norrie J, O'Dwyer PJ. Long-term follow-up of patients with a painless inguinal hernia from a randomized clinical trial. Br J Surg. 2011 Apr;98(4):596-9.
http://www.ncbi.nlm.nih.gov/pubmed/21656724?tool=bestpractice.com
In one study in the Netherlands (496 male patients; >50 years of age), 2-year postoperative complication and recurrence rates did not differ significantly between 99 (37.7%) of 262 patients randomized to watchful waiting and who subsequently underwent surgical repair, and patients who were originally assigned to elective repair (8.1% vs. 15.0%, P = 0.106; 7.1% vs. 8.9%, P = 0.668, respectively).[59]de Goede B, Wijsmuller AR, van Ramshorst GH, et al. Watchful waiting versus surgery of mildly symptomatic or asymptomatic inguinal hernia in men aged 50 years and older: a randomized controlled trial. Ann Surg. 2018 Jan;267(1):42-9.
http://www.ncbi.nlm.nih.gov/pubmed/28350567?tool=bestpractice.com
Acute hernia complications, such as bowel obstruction and incarceration/strangulation, occur rarely with a watchful waiting strategy. One review recommended informing patients that the surgical emergency rate during watchful waiting is 1.8 per 1000 person-years.[60]Montgomery J, Dimick JB, Telem DA. Management of groin hernias in adults-2018. JAMA. 2018 Sep 11;320(10):1029-30.
http://www.ncbi.nlm.nih.gov/pubmed/30128503?tool=bestpractice.com
Patients should be advised to seek medical attention immediately if they develop signs and symptoms of serious complication (e.g., abdominal pain, nausea, vomiting, and constipation).[54]Fitzgibbons RJ Jr, Giobbie-Hurder A, Gibbs JO, et al. Watchful waiting vs repair of inguinal hernia in minimally symptomatic men: a randomized clinical trial. JAMA. 2006 Jan 18;295(3):285-92.
http://jama.ama-assn.org/content/295/3/285.long
http://www.ncbi.nlm.nih.gov/pubmed/16418463?tool=bestpractice.com
Surgery
Primary-tissue (non-mesh) repair (e.g., using Bassini, Cooper ligament or Shouldice technique) was the mainstay of surgical treatment of inguinal hernia prior to 1990; however, these techniques have mostly been superseded by open-mesh repair using the Lichtenstein technique or by minimally invasive laparo-endoscopic repair.[61]Lichtenstein IL, Shulman AG, Amid PK, et al. The tension-free hernioplasty. Am J Surg. 1989 Feb;157(2):188-93.
http://www.ncbi.nlm.nih.gov/pubmed/2916733?tool=bestpractice.com
All three approaches seem to be equally efficacious.[62]Lyu Y, Cheng Y, Wang B, et al. Comparison of endoscopic surgery and Lichtenstein repair for treatment of inguinal hernias: a network meta-analysis. Medicine (Baltimore). 2020 Feb;99(6):e19134.
https://www.doi.org/10.1097/MD.0000000000019134
http://www.ncbi.nlm.nih.gov/pubmed/32028439?tool=bestpractice.com
[63]Aiolfi A, Cavalli M, Micheletto G, et al. Primary inguinal hernia: systematic review and Bayesian network meta-analysis comparing open, laparoscopic transabdominal preperitoneal, totally extraperitoneal, and robotic preperitoneal repair. Hernia. 2019 Jun;23(3):473-84.
https://www.doi.org/10.1007/s10029-019-01964-2
http://www.ncbi.nlm.nih.gov/pubmed/31089835?tool=bestpractice.com
Open surgical repair
The Lichtenstein technique involves placing a tension-free polypropylene mesh prosthesis (approximately 5 cm x 12 cm in size) over the posterior wall of the inguinal floor and internal oblique from the pubis to the iliac spine, encircling the cord structures through a keyhole.[61]Lichtenstein IL, Shulman AG, Amid PK, et al. The tension-free hernioplasty. Am J Surg. 1989 Feb;157(2):188-93.
http://www.ncbi.nlm.nih.gov/pubmed/2916733?tool=bestpractice.com
The mesh must be secured to the pubis, shelving edge of inguinal ligament, and internal oblique fascia. Inguinal numbness, which may gradually abate over time, is the most common side effect of this procedure.
Open preperitoneal mesh repair, in which the preperitoneal space is opened for mesh placement through a small suprapubic or inguinal incision, is a safe and efficacious alternative to Lichtenstein mesh repair.[64]Li J, Ji Z, Cheng T. Comparison of open preperitoneal and Lichtenstein repair for inguinal hernia repair: a meta-analysis of randomized controlled trials. Am J Surg. 2012 Nov;204(5):769-78.
http://www.ncbi.nlm.nih.gov/pubmed/22621832?tool=bestpractice.com
[65]Sharma P, Boyers D, Scott N, et al. The clinical effectiveness and cost-effectiveness of open mesh repairs in adults presenting with a clinically diagnosed primary unilateral inguinal hernia who are operated in an elective setting: systematic review and economic evaluation. Health Technol Assess. 2015 Nov;19(92):1-142.
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0094801
http://www.ncbi.nlm.nih.gov/pubmed/26556776?tool=bestpractice.com
The plug-and-patch system is a less desirable open-mesh repair technique. This procedure involves inserting a cone-shaped plug of polypropylene mesh into the defect, secured to the internal ring in the case of indirect hernia, or the neck of the defect in direct hernia, which can be covered by an additional flat mesh prosthesis. This technique is not performed as often as the Lichtenstein technique due to higher rates of complications, including migration of the plug, with erosion into bowel or bladder.[66]Sanjay P, Watt DG, Ogston SA, et al. Meta-analysis of Prolene Hernia System mesh versus Lichtenstein mesh in open inguinal hernia repair. Surgeon. 2012 Oct;10(5):283-9.
http://www.ncbi.nlm.nih.gov/pubmed/22824553?tool=bestpractice.com
[67]Ishiguro Y, Horie H, Satoh H, et al. Colocutaneous fistula after left inguinal hernia repair using the mesh plug technique. Surgery. 2009 Jan;145(1):120-1.
http://www.ncbi.nlm.nih.gov/pubmed/19081484?tool=bestpractice.com
Open-mesh repair is associated with a much lower recurrence rate than primary-tissue repair or other non-mesh repair techniques.[9]Itani KMF, Fitzgibbons R. Approach to groin hernias. JAMA Surg. 2019 Jun 1;154(6):551-2.
https://www.doi.org/10.1001/jamasurg.2018.5564
http://www.ncbi.nlm.nih.gov/pubmed/30865244?tool=bestpractice.com
[68]Lockhart K, Dunn D, Teo S, et al. Mesh versus non-mesh for inguinal and femoral hernia repair. Cochrane Database Syst Rev. 2018 Sep 13;(9):CD011517.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011517.pub2/full
http://www.ncbi.nlm.nih.gov/pubmed/30209805?tool=bestpractice.com
[69]Scott N, Go PM, Graham P, et al. Open mesh versus non‐mesh for groin hernia repair. Cochrane Database Syst Rev. 2001;(3):CD002197.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD002197/full
[
]
How does mesh compare with non‐mesh for inguinal hernia repair?/cca.html?targetUrl=https://www.cochranelibrary.com/cca/doi/10.1002/cca.2416/fullShow me the answer[Evidence A]da3ae3e4-fa0b-4bab-9be8-3e0029604a3fccaAHow does mesh compare with non‐mesh for inguinal hernia repair? It is also a low-risk procedure that can be done under spinal, general, or local anesthesia with mild sedation. If feasible, local anesthesia may be preferred to spinal anesthesia.[70]Prakash D, Heskin L, Doherty S, et al. Local anaesthesia versus spinal anaesthesia in inguinal hernia repair: a systematic review and meta-analysis. Surgeon. 2017 Feb;15(1):47-57.
http://www.ncbi.nlm.nih.gov/pubmed/26895656?tool=bestpractice.com
Otherwise, spinal or general anesthesia are equally good choices.[71]Li L, Pang Y, Wang Y, et al. Comparison of spinal anesthesia and general anesthesia in inguinal hernia repair in adult: a systematic review and meta-analysis. BMC Anesthesiol. 2020 Mar 10;20(1):64.
https://www.doi.org/10.1186/s12871-020-00980-5
http://www.ncbi.nlm.nih.gov/pubmed/32156258?tool=bestpractice.com
Minimally invasive (laparoscopic) surgical repair
Minimally invasive laparoscopic mesh repair is an alternative to open-mesh repair. Laparoscopic mesh repair requires general anesthesia, and is technically more challenging and has a longer learning curve for the surgeon than open-mesh repair. It involves placing a large (approximately 12 cm diameter) mesh prosthesis in the preperitoneal space, extending from pubis to iliac spine and overlying the iliac vessels.[72]Neumayer L, Giobbie-Hurder A, Jonasson O, et al. Open mesh versus laparoscopic mesh repair of inguinal hernia. N Engl J Med. 2004 Apr 29;350(18):1819-27.
http://www.nejm.org/doi/full/10.1056/NEJMoa040093#t=article
http://www.ncbi.nlm.nih.gov/pubmed/15107485?tool=bestpractice.com
[73]Haifler M, Benjamin B, Ghinea R, Avital S. The impact of previous laparoscopic inguinal hernia repair on radical prostatectomy. J Endourol. 2012 Nov;26(11):1458-62.
http://www.ncbi.nlm.nih.gov/pubmed/22788410?tool=bestpractice.com
Advantages of laparoscopic mesh repair compared with open-mesh repair include:[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[9]Itani KMF, Fitzgibbons R. Approach to groin hernias. JAMA Surg. 2019 Jun 1;154(6):551-2.
https://www.doi.org/10.1001/jamasurg.2018.5564
http://www.ncbi.nlm.nih.gov/pubmed/30865244?tool=bestpractice.com
[74]McCormack K, Scorr NW, Go PM, et al. EU hernia Trialists Collaboration. Laparoscopic techniques versus open techniques for inguinal hernia repair. Cochrane Database Syst Rev. 2003;(1):CD001785.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001785/full
http://www.ncbi.nlm.nih.gov/pubmed/12535413?tool=bestpractice.com
[75]Ger R. The management of certain abdominal herniae by intra-abdominal closure of the neck of the sac. Preliminary communication. Ann R Coll Surg Engl. 1982 Sep;64(5):342-4.
http://www.ncbi.nlm.nih.gov/pubmed/7114772?tool=bestpractice.com
[76]Köckerling F, Stechemesser B, Hukauf M, et al. TEP versus Lichtenstein: Which technique is better for the repair of primary unilateral inguinal hernias in men? Surg Endosc. 2016 Aug;30(8):3304-13.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956717
http://www.ncbi.nlm.nih.gov/pubmed/26490771?tool=bestpractice.com
[77]Westin L, Wollert S, Ljungdahl M, et al. Less pain 1 year after total extra-peritoneal repair compared with Lichtenstein using local anesthesia: data from a randomized controlled clinical trial. Ann Surg. 2016 Feb;263(2):240-3.
http://www.ncbi.nlm.nih.gov/pubmed/26079901?tool=bestpractice.com
[78]Eklund A, Montgomery A, Bergkvist L, et al. Chronic pain 5 years after randomized comparison of laparoscopic and Lichtenstein inguinal hernia repair. Br J Surg. 2010 Apr;97(4):600-8.
http://www.ncbi.nlm.nih.gov/pubmed/20186889?tool=bestpractice.com
Recurrence and complication rates are similar to open-mesh repair, although patients undergoing laparoscopic procedures may experience less chronic inguinal pain than those who have a Lichtenstein procedure.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[79]Koning GG, Wetterslev J, van Laarhoven CJ, et al. The totally extraperitoneal method versus Lichtenstein's technique for inguinal hernia repair: a systematic review with meta-analyses and trial sequential analyses of randomized clinical trials. PLoS One. 2013;8(1):e52599.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543416/pdf/pone.0052599.pdf
http://www.ncbi.nlm.nih.gov/pubmed/23349689?tool=bestpractice.com
[80]Scheuermann U, Niebisch S, Lyros O, et al. Transabdominal preperitoneal (TAPP) versus Lichtenstein operation for primary inguinal hernia repair - a systematic review and meta-analysis of randomized controlled trials. BMC Surg. 2017 May 10;17(1):55.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424320
http://www.ncbi.nlm.nih.gov/pubmed/28490321?tool=bestpractice.com
Risk of serious injury to bowel, bladder, and vascular structure is higher with laparoscopic procedures.[81]O'Reilly EA, Burke JP, O'Connell PR. A meta-analysis of surgical morbidity and recurrence after laparoscopic and open repair of primary unilateral inguinal hernia. Ann Surg. 2012 May;255(5):846-53.
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0047990
http://www.ncbi.nlm.nih.gov/pubmed/22470068?tool=bestpractice.com
There are two laparoscopic approaches: totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP). The TEP procedure involves opening the preperitoneal space, usually with a balloon device, to create a space in which a large contoured mesh patch covering the inguinal area from below is placed. The TAPP procedure involves placing the laparoscope into the peritoneal cavity and incising the peritoneum under the inguinal canal to open the preperitoneal space for a mesh placement, after which the peritoneal incision is closed over the mesh. Each approach has its advocates, but there is no clear superiority of one approach over the other for repair of primary unilateral inguinal hernia, or for recurrent inguinal hernia repair following previous open primary repair.[81]O'Reilly EA, Burke JP, O'Connell PR. A meta-analysis of surgical morbidity and recurrence after laparoscopic and open repair of primary unilateral inguinal hernia. Ann Surg. 2012 May;255(5):846-53.
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0047990
http://www.ncbi.nlm.nih.gov/pubmed/22470068?tool=bestpractice.com
[82]Köckerling F, Bittner R, Kuthe A, et al. TEP or TAPP for recurrent inguinal hernia repair - register-based comparison of the outcome. Surg Endosc. 2017 Oct;31(10):3872-82.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636847
http://www.ncbi.nlm.nih.gov/pubmed/28160069?tool=bestpractice.com
Choice of technique may be influenced by the surgeon’s skills and experience.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
Choice of repair
The decision to offer the patient an open or laparoscopic repair depends on the anatomy of the hernia, whether the hernia is primary or recurrent, the experience of the surgeon, and the wishes of the patient.[74]McCormack K, Scorr NW, Go PM, et al. EU hernia Trialists Collaboration. Laparoscopic techniques versus open techniques for inguinal hernia repair. Cochrane Database Syst Rev. 2003;(1):CD001785.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001785/full
http://www.ncbi.nlm.nih.gov/pubmed/12535413?tool=bestpractice.com
[81]O'Reilly EA, Burke JP, O'Connell PR. A meta-analysis of surgical morbidity and recurrence after laparoscopic and open repair of primary unilateral inguinal hernia. Ann Surg. 2012 May;255(5):846-53.
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0047990
http://www.ncbi.nlm.nih.gov/pubmed/22470068?tool=bestpractice.com
[83]National Institute for Health and Care Excellence. Laparoscopic surgery for inguinal hernia repair. Sep 2004 [internet publication].
https://www.nice.org.uk/guidance/TA83
[84]Wantz GE, Fischer E. Unilateral giant prosthetic reinforcement of the visceral sac. In: Bendavid R, ed. Abdominal wall hernias. New York: Springer-Verlag; 2001:219-27.[85]Itani KM, Fitzgibbons R Jr, Awad SS, et al. Management of recurrent inguinal hernias. J Am Coll Surg. 2009 Nov;209(5):653-8.
http://www.ncbi.nlm.nih.gov/pubmed/19854408?tool=bestpractice.com
Risks and complications vary between the two approaches.[76]Köckerling F, Stechemesser B, Hukauf M, et al. TEP versus Lichtenstein: Which technique is better for the repair of primary unilateral inguinal hernias in men? Surg Endosc. 2016 Aug;30(8):3304-13.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956717
http://www.ncbi.nlm.nih.gov/pubmed/26490771?tool=bestpractice.com
[81]O'Reilly EA, Burke JP, O'Connell PR. A meta-analysis of surgical morbidity and recurrence after laparoscopic and open repair of primary unilateral inguinal hernia. Ann Surg. 2012 May;255(5):846-53.
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0047990
http://www.ncbi.nlm.nih.gov/pubmed/22470068?tool=bestpractice.com
Open surgery is the most common, accounting for the majority of inguinal hernia repairs.[72]Neumayer L, Giobbie-Hurder A, Jonasson O, et al. Open mesh versus laparoscopic mesh repair of inguinal hernia. N Engl J Med. 2004 Apr 29;350(18):1819-27.
http://www.nejm.org/doi/full/10.1056/NEJMoa040093#t=article
http://www.ncbi.nlm.nih.gov/pubmed/15107485?tool=bestpractice.com
[83]National Institute for Health and Care Excellence. Laparoscopic surgery for inguinal hernia repair. Sep 2004 [internet publication].
https://www.nice.org.uk/guidance/TA83
An open approach may be preferable to a laparoscopic approach for a unilateral primary hernia, although a laparoscopic approach may be appropriate for some patients, pending availability of sufficient resources and surgical expertise.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
Laparoscopic repair may be preferable for patients with recurrence after open repair, or for those with bilateral hernias that can be repaired at the same time.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[72]Neumayer L, Giobbie-Hurder A, Jonasson O, et al. Open mesh versus laparoscopic mesh repair of inguinal hernia. N Engl J Med. 2004 Apr 29;350(18):1819-27.
http://www.nejm.org/doi/full/10.1056/NEJMoa040093#t=article
http://www.ncbi.nlm.nih.gov/pubmed/15107485?tool=bestpractice.com
[74]McCormack K, Scorr NW, Go PM, et al. EU hernia Trialists Collaboration. Laparoscopic techniques versus open techniques for inguinal hernia repair. Cochrane Database Syst Rev. 2003;(1):CD001785.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001785/full
http://www.ncbi.nlm.nih.gov/pubmed/12535413?tool=bestpractice.com
[83]National Institute for Health and Care Excellence. Laparoscopic surgery for inguinal hernia repair. Sep 2004 [internet publication].
https://www.nice.org.uk/guidance/TA83
[85]Itani KM, Fitzgibbons R Jr, Awad SS, et al. Management of recurrent inguinal hernias. J Am Coll Surg. 2009 Nov;209(5):653-8.
http://www.ncbi.nlm.nih.gov/pubmed/19854408?tool=bestpractice.com
[86]Wauschkuhn CA, Schwarz J, Boekeler U, et al. Laparoscopic inguinal hernia repair: gold standard in bilateral hernia repair? Results of more than 2800 patients in comparison to literature. Surg Endosc. 2010 Dec;24(12):3026-30.
http://www.ncbi.nlm.nih.gov/pubmed/20454807?tool=bestpractice.com
Two recent brief reviews offer treatment decision algorithms.[9]Itani KMF, Fitzgibbons R. Approach to groin hernias. JAMA Surg. 2019 Jun 1;154(6):551-2.
https://www.doi.org/10.1001/jamasurg.2018.5564
http://www.ncbi.nlm.nih.gov/pubmed/30865244?tool=bestpractice.com
[60]Montgomery J, Dimick JB, Telem DA. Management of groin hernias in adults-2018. JAMA. 2018 Sep 11;320(10):1029-30.
http://www.ncbi.nlm.nih.gov/pubmed/30128503?tool=bestpractice.com
The most recent meta-analysis found all three most common repairs to be comparable.[62]Lyu Y, Cheng Y, Wang B, et al. Comparison of endoscopic surgery and Lichtenstein repair for treatment of inguinal hernias: a network meta-analysis. Medicine (Baltimore). 2020 Feb;99(6):e19134.
https://www.doi.org/10.1097/MD.0000000000019134
http://www.ncbi.nlm.nih.gov/pubmed/32028439?tool=bestpractice.com
Mesh prosthesis
Polypropylene mesh is the most popular prosthetic material used in hernia repair. It is important to use a large enough prosthesis. Studies with long-term follow-up demonstrate no advantage to using newer lightweight meshes over older heavier versions.[87]Burgmans JP, Voorbrood CE, Simmermacher RK, et al. Long-term results of a randomized double-blinded prospective trial of a lightweight (Ultrapro) versus a heavyweight mesh (Prolene) in laparoscopic total extraperitoneal inguinal hernia repair (TULP-trial). Ann Surg. 2016 May;263(5):862-6.
http://www.ncbi.nlm.nih.gov/pubmed/26779980?tool=bestpractice.com
[88]Carro JLP, Riu SV, Lojo BR, et al. Randomized clinical trial comparing low density versus high density meshes in patients with bilateral inguinal hernia. Am Surg. 2017 Dec 1;83(12):1352-6.
http://www.ncbi.nlm.nih.gov/pubmed/29336753?tool=bestpractice.com
Low-cost mosquito netting has been successfully used in low-income countries in sub-Saharan Africa, and can be used in developing countries.[89]Löfgren J, Nordin P, Ibingira C, et al. A randomized trial of low-cost mesh in groin hernia repair. N Engl J Med. 2016 Jan 14;374(2):146-53.
http://www.nejm.org/doi/full/10.1056/NEJMoa1505126
http://www.ncbi.nlm.nih.gov/pubmed/26760085?tool=bestpractice.com
[90]Patterson T, Currie P, Patterson S, et al. A systematic review and meta-analysis of the post-operative adverse effects associated with mosquito net mesh in comparison to commercial hernia mesh for inguinal hernia repair in low income countries. Hernia. 2017 Jun;21(3):397-405.
http://www.ncbi.nlm.nih.gov/pubmed/28409276?tool=bestpractice.com
However, an appropriate type of netting may no longer be readily available in developing countries.[91]Löfgren J, Beard J, Ashley T. Groin hernia surgery in low-resource settings - a problem still unsolved. N Engl J Med. 2018 Apr 5;378(14):1357-8.
https://www.doi.org/10.1056/NEJMc1800621
http://www.ncbi.nlm.nih.gov/pubmed/29617581?tool=bestpractice.com
If mesh becomes infected, it must usually be removed. Recurrence of hernia after removal of infected mesh is uncommon.[92]Rehman S, Khan S, Pervaiz A, et al. Recurrence of inguinal herniae following removal of infected prostheses. Hernia. 2012 Apr;16(2):123-6.
http://www.ncbi.nlm.nih.gov/pubmed/21858435?tool=bestpractice.com
Bioprostheses obtained from cadaveric skin or from porcine intestinal mucosa may be used in a hernia repair that is associated with contaminated surgical fields.[93]Albo D, Awad SS, Berger DH, et al. Decellularized human cadaveric dermis provides a safe alternative for primary inguinal hernia repair in contaminated surgical fields. Am J Surg. 2006 Nov;192(5):e12-7.
http://www.ncbi.nlm.nih.gov/pubmed/17071174?tool=bestpractice.com
[94]Gentile P, Colicchia GM, Nicoli F, et al. Complex abdominal wall repair using a porcine dermal matrix. Surg Innov. 2013 Dec;20(6):NP12-5.
http://www.ncbi.nlm.nih.gov/pubmed/22006210?tool=bestpractice.com
In this situation, the use of local tissue is associated with high recurrence rate, and standard prosthetic mesh is associated with significant risk of infection. Bioprostheses are not used routinely in elective inguinal hernia repair.
Initial concerns regarding postoperative pain attributed to mesh prostheses have been shown to be unwarranted.[95]Öberg S, Andresen K, Klausen TW, et al. Chronic pain after mesh versus nonmesh repair of inguinal hernias: A systematic review and a network meta-analysis of randomized controlled trials. Surgery. 2018 May;163(5):1151-9.
https://www.doi.org/10.1016/j.surg.2017.12.017
http://www.ncbi.nlm.nih.gov/pubmed/29506882?tool=bestpractice.com
Likewise, concerns regarding infertility have been disproven as well.[96]Kohl AP, Andresen K, Rosenberg J. Male fertility after inguinal hernia mesh repair: a national register study. Ann Surg. 2018 Aug;268(2):374-8.
https://www.doi.org/10.1097/SLA.0000000000002423
http://www.ncbi.nlm.nih.gov/pubmed/28704231?tool=bestpractice.com
[97]Dong Z, Kujawa SA, Wang C, et al. Does the use of hernia mesh in surgical inguinal hernia repairs cause male infertility? A systematic review and descriptive analysis. Reprod Health. 2018 Apr 23;15(1):69.
https://www.doi.org/10.1186/s12978-018-0510-y
http://www.ncbi.nlm.nih.gov/pubmed/29688866?tool=bestpractice.com
Incarcerated or strangulated hernia
A hernia is incarcerated when the hernia content cannot be reduced into the abdominal cavity. Bowel or omentum passing through the tight hernia neck can become trapped and edematous, which can lead to further swelling and fluid sequestration in the bowel lumen. This can cause bowel obstruction, impairment of the blood supply in the bowel, and eventually strangulation.
Emergent surgical repair is indicated for acute incarcerated hernia.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
The optimal surgical approach is not known,[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
but a laparoscopic approach may be considered in the absence of strangulation.[98]Birindelli A, Sartelli M, Di Saverio S, et al. 2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias. World J Emerg Surg. 2017 Aug 7;12:37.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545868
http://www.ncbi.nlm.nih.gov/pubmed/28804507?tool=bestpractice.com
An incarcerated hernia may be reduced with the patient sedated, but care should be taken to avoid pushing a nonviable loop of the bowel from the hernia sac back into the peritoneal cavity (hernia en masse). Mesh repair is indicated if the bowel is viable, but non-mesh repair is indicated if the bowel is nonviable or if viability is in doubt.
Patients should undergo emergent open surgical repair for suspected strangulated inguinal hernia because the bowel may necrose if the underlying obstruction is not relieved promptly.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[98]Birindelli A, Sartelli M, Di Saverio S, et al. 2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias. World J Emerg Surg. 2017 Aug 7;12:37.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545868
http://www.ncbi.nlm.nih.gov/pubmed/28804507?tool=bestpractice.com
Adequate fluid resuscitation, nasogastric intubation, and urethral catheterization are often required. In the absence of necrosis or contamination, the bowel can be reduced and the hernia repaired with a mesh.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[98]Birindelli A, Sartelli M, Di Saverio S, et al. 2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias. World J Emerg Surg. 2017 Aug 7;12:37.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545868
http://www.ncbi.nlm.nih.gov/pubmed/28804507?tool=bestpractice.com
[99]Duan SJ, Qiu SB, Ding NY, et al. Prosthetic mesh repair in the emergency management of acutely strangulated groin hernias with grade I bowel necrosis: a rational choice. Am Surg. 2018 Feb 1;84(2):215-9.
http://www.ncbi.nlm.nih.gov/pubmed/29580348?tool=bestpractice.com
If nonviable bowel (gangrenous) or contamination is found during surgery, bowel resection is usually required, and a non-mesh primary tissue repair of the hernia performed.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[98]Birindelli A, Sartelli M, Di Saverio S, et al. 2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias. World J Emerg Surg. 2017 Aug 7;12:37.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545868
http://www.ncbi.nlm.nih.gov/pubmed/28804507?tool=bestpractice.com
Mesh repair should be avoided in this situation due to the risk of mesh infection.
Prophylactic antibiotic therapy
Use of antibiotic prophylaxis during uncomplicated hernia repair is controversial, particularly as the rate of surgical site infection is low.
In a low-risk environment (≤5% incidence of wound infection), antibiotic prophylaxis is:[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[100]Orelio CC, van Hessen C, Sanchez-Manuel FJ, et al. Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair. Cochrane Database Syst Rev. 2020 Apr 21;4:CD003769.
https://www.doi.org/10.1002/14651858.CD003769.pub5
http://www.ncbi.nlm.nih.gov/pubmed/32315460?tool=bestpractice.com
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What are the effects of antibiotic prophylaxis for preventing wound infection in adults undergoing open inguinal or femoral hernioplasty surgery?/cca.html?targetUrl=https://www.cochranelibrary.com/cca/doi/10.1002/cca.3131/fullShow me the answer
In a high-risk environment (>5% incidence of wound infection), antibiotic prophylaxis is recommended for any patient undergoing open-mesh repair.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
Antibiotic prophylaxis for laparoscopic repair is not recommended.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
[101]Köckerling F, Bittner R, Jacob D, et al. Do we need antibiotic prophylaxis in endoscopic inguinal hernia repair? Results of the Herniamed Registry. Surg Endosc. 2015 Dec;29(12):3741-9.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648957
http://www.ncbi.nlm.nih.gov/pubmed/25786905?tool=bestpractice.com
[100]Orelio CC, van Hessen C, Sanchez-Manuel FJ, et al. Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair. Cochrane Database Syst Rev. 2020 Apr 21;4:CD003769.
https://www.doi.org/10.1002/14651858.CD003769.pub5
http://www.ncbi.nlm.nih.gov/pubmed/32315460?tool=bestpractice.com
Adult patients with acutely incarcerated/strangulated inguinal hernias should receive antibiotic prophylaxis.[2]HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018 Feb;22(1):1-165.
https://link.springer.com/article/10.1007/s10029-017-1668-x
http://www.ncbi.nlm.nih.gov/pubmed/29330835?tool=bestpractice.com
Nevertheless, antibiotic use is common in the US.
Choice of antibiotic regimen depends on local guidance. A single dose of a cephalosporin (e.g., cefazolin) has been recommended. For patients known to have MRSA, vancomycin can be added. Clindamycin or vancomycin may be used as an alternative to cefazolin in patients who are allergic to beta-lactam antibiotics.[102]Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm. 2013 Feb 1;70(3):195-283.
http://www.ncbi.nlm.nih.gov/pubmed/23327981?tool=bestpractice.com
A meta-analysis found that beta‐lactam/beta‐lactamase inhibitors and first‐generation cephalosporins appear to be the most effective antibiotics for adult patients undergoing inguinal hernia repair.[103]Boonchan T, Wilasrusmee C, McEvoy M, et al. Network meta-analysis of antibiotic prophylaxis for prevention of surgical-site infection after groin hernia surgery. Br J Surg. 2017 Jan;104(2):e106-17.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299528
http://www.ncbi.nlm.nih.gov/pubmed/28121028?tool=bestpractice.com
In the absence of definitive evidence, single-dose antimicrobial prophylaxis with a first-generation cephalosporin is an acceptable approach for open-mesh repair.
Recurrence following surgery
Prior to the introduction of mesh repairs, recurrence rates following primary inguinal hernia repair were estimated to be between 10% and 30%.[104]Gopal SV, Warrier A. Recurrence after groin hernia repair-revisited. Int J Surg. 2013;11(5):374-7.
https://www.journal-surgery.net/article/S1743-9191(13)00087-3/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/23557981?tool=bestpractice.com
Recurrence rates after mesh repairs, either open or laparoscopic, are much lower at less than 2%.[104]Gopal SV, Warrier A. Recurrence after groin hernia repair-revisited. Int J Surg. 2013;11(5):374-7.
https://www.journal-surgery.net/article/S1743-9191(13)00087-3/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/23557981?tool=bestpractice.com
[105]Belyansky I, Tsirline VB, Klima DA, et al. Prospective, comparative study of postoperative quality of life in TEP, TAPP, and modified Lichtenstein repairs. Ann Surg. 2011 Nov;254(5):709-14.
http://www.ncbi.nlm.nih.gov/pubmed/21997807?tool=bestpractice.com
[106]Shulman AG, Amid PK, Lichtenstein IL.The safety of mesh repair for primary inguinal hernias: results of 3,019 operations from five diverse surgical sources. Am Surg. 1992 Apr;58(4):255-7.
http://www.ncbi.nlm.nih.gov/pubmed/1586085?tool=bestpractice.com
One systematic review and meta-analysis found that one hernia recurrence could be prevented for every 46 mesh repairs rather than non-mesh repairs.[68]Lockhart K, Dunn D, Teo S, et al. Mesh versus non-mesh for inguinal and femoral hernia repair. Cochrane Database Syst Rev. 2018 Sep 13;(9):CD011517.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011517.pub2/full
http://www.ncbi.nlm.nih.gov/pubmed/30209805?tool=bestpractice.com
The risk of developing a new hernia on the contralateral side after repair on one side has been estimated to be 7% to 11% over ten years.[107]Zheng R, Altieri MS, Yang J, et al. Long-term incidence of contralateral primary hernia repair following unilateral inguinal hernia repair in a cohort of 32,834 patients. Surg Endosc. 2017 Feb;31(2):817-22.
http://www.ncbi.nlm.nih.gov/pubmed/27369285?tool=bestpractice.com
Truss
A truss (or a wearable device that compresses the tissues over the inguinal canal) is a traditional nonsurgical treatment for inguinal hernia. If used, it should be applied after the hernia is reduced and when symptoms have been alleviated. A truss should keep the hernia reduced so that pain and discomfort are minimized. However, many patients find them cumbersome to use. Furthermore, hernia accidents (where the hernia escapes from the truss and may become strangulated by the truss) and atrophy of the skin under the truss can occur. A truss is not a cure. Long-term use should be reserved for patients in whom surgery is not appropriate, whose life expectancy is limited, or who refuse surgical repair.