Volume depletion occurs frequently in paediatric patients. Data on epidemiology from all causes are not available, but some useful information can be extrapolated from information on two of the most common causes, gastroenteritis and trauma. In the US, gastroenteritis accounts for more than 1.5 million outpatient visits, 200,000 admissions to hospital, and about 300 deaths each year.[1]Tucker AW, Haddix AC, Bresee JS, et al. Cost-effectiveness analysis of a rotavirus immunization program for the United States. JAMA. 1998;279:1371-1376.
http://jama.ama-assn.org/cgi/content/full/279/17/1371
http://www.ncbi.nlm.nih.gov/pubmed/9582045?tool=bestpractice.com
[2]McConnochie KM, Conners GP, Lu E, et al. How commonly are children hospitalized for dehydration eligible for care in alternative settings? Arch Pediatr Adolesc Med. 1999;153:1233-1241.
http://jamanetwork.com/journals/jamapediatrics/fullarticle/348233
http://www.ncbi.nlm.nih.gov/pubmed/10591299?tool=bestpractice.com
Worldwide, around 444,000 children under 5 years of age die each year from diarrhoea.[3]World Health Organization. Diarrhoeal disease. Mar 2024 [internet publication].
https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease
Globally, there are around 1.7 billion cases of diarrhoeal illness each year; it is the third leading cause of death in children under 5 years old.[3]World Health Organization. Diarrhoeal disease. Mar 2024 [internet publication].
https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease
Trauma is a common cause of death in children 5 years and older.[4]Villavicencio F, Perin J, Eilerts-Spinelli H, et al. Global, regional, and national causes of death in children and adolescents younger than 20 years: an open data portal with estimates for 2000-21. Lancet Glob Health. 2024 Jan;12(1):e16-7.
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(23)00496-5/fulltext
A substantial portion of those with significant injuries present with some degree of volume depletion from external and occult bleeding, crush injuries, and burns. Other causes of volume depletion in children are less common, but have significant impact on child health and illness.