See Management approach for recommendations on maternal and fetal monitoring during pregnancy and the intrapartum period.
A diagnosis of GDM mandates follow-up assessments of glycemia postpartum; but unfortunately rates of postpartum screening for diabetes mellitus in women with a history of GDM are low, with fewer than half of women receiving screening.[1]American Diabetes Association. Introduction and methodology: standards of care in diabetes - 2024. Diabetes Care 2024;47(Suppl. 1):S1-S4.
https://diabetesjournals.org/care/issue/47/Supplement_1
[48]American College of Obstetricians and Gynecologists. ACOG clinical practice update: screening for gestational and pregestational diabetes in pregnancy and postpartum. Obstet Gynecol. 2024;144(1):e20-3.
https://journals.lww.com/greenjournal/abstract/2024/07000/acog_clinical_practice_update__screening_for.34.aspx
[51]American College of Obstetricians and Gynecologists. ACOG practice bulletin no.190: gestational diabetes mellitus. Feb 2018 [internet publication].
https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2018/02/gestational-diabetes-mellitus
[139]Tovar A, Chasan-Taber L, Eggleston E, et al. Postpartum screening for diabetes among women with a history of gestational diabetes mellitus. Prev Chronic Dis. 2011 Nov;8(6):A124.
https://www.cdc.gov/pcd/issues/2011/nov/11_0031.htm
http://www.ncbi.nlm.nih.gov/pubmed/22005617?tool=bestpractice.com
Studies have suggested that there are multiple reasons for this, such as transportation, lack of childcare, limited coverage for medical care, and lack of understanding of the risks of diabetes mellitus.[48]American College of Obstetricians and Gynecologists. ACOG clinical practice update: screening for gestational and pregestational diabetes in pregnancy and postpartum. Obstet Gynecol. 2024;144(1):e20-3.
https://journals.lww.com/greenjournal/abstract/2024/07000/acog_clinical_practice_update__screening_for.34.aspx
Women should be screened with a 75-g oral glucose tolerance test (OGTT), using nonpregnant OGTT criteria, either in the immediate postpartum period (during delivery hospitalization) or at 4-12 weeks postpartum. The OGTT is preferred as a more sensitive test than fasting plasma glucose or HbA1c.[1]American Diabetes Association. Introduction and methodology: standards of care in diabetes - 2024. Diabetes Care 2024;47(Suppl. 1):S1-S4.
https://diabetesjournals.org/care/issue/47/Supplement_1
[48]American College of Obstetricians and Gynecologists. ACOG clinical practice update: screening for gestational and pregestational diabetes in pregnancy and postpartum. Obstet Gynecol. 2024;144(1):e20-3.
https://journals.lww.com/greenjournal/abstract/2024/07000/acog_clinical_practice_update__screening_for.34.aspx
However, given the low rates of oral glucose tolerance test uptake, screening with hemoglobin HbA1c or fasting glucose should be considered within the first year postpartum for those who do not complete an oral glucose tolerance test.[123]Lewey J, Beckie TM, Brown HL, et al. Opportunities in the postpartum period to reduce cardiovascular disease risk after adverse pregnancy outcomes: a scientific statement from the American Heart Association. Circulation. 2024 Feb 13;149(7):e330-46.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11185178
http://www.ncbi.nlm.nih.gov/pubmed/38346104?tool=bestpractice.com
Those with impaired testing, but which is not diagnostic of diabetes mellitus, should be screened annually.[51]American College of Obstetricians and Gynecologists. ACOG practice bulletin no.190: gestational diabetes mellitus. Feb 2018 [internet publication].
https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2018/02/gestational-diabetes-mellitus
Those with initially normal postpartum OGTT studies should be retested at least every 3 years.[1]American Diabetes Association. Introduction and methodology: standards of care in diabetes - 2024. Diabetes Care 2024;47(Suppl. 1):S1-S4.
https://diabetesjournals.org/care/issue/47/Supplement_1
[51]American College of Obstetricians and Gynecologists. ACOG practice bulletin no.190: gestational diabetes mellitus. Feb 2018 [internet publication].
https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2018/02/gestational-diabetes-mellitus
Offspring of women with GDM should be monitored closely for development of diabetes and diabetes risk factors (obesity, sedentary lifestyle).[137]Lowe WL Jr, Lowe LP, Kuang A, et al; HAPO Follow-up Study Cooperative Research Group. Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study. Diabetologia. 2019 Jan 15;62(4):598-610.
https://link.springer.com/article/10.1007%2Fs00125-018-4809-6
http://www.ncbi.nlm.nih.gov/pubmed/30648193?tool=bestpractice.com
[140]Scholtens DM, Kuang A, Lowe LP, et al; HAPO Follow-Up Study Cooperative Research Group. Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): maternal glycemia and childhood glucose metabolism. Diabetes Care. 2019 Jan 7;42(3):381-92.
https://care.diabetesjournals.org/content/42/3/381.long
http://www.ncbi.nlm.nih.gov/pubmed/30617141?tool=bestpractice.com