Complex regional pain syndrome

Budapest diagnostic criteria, 2004​[1]Harden RN, Bruehl SP, Stanton-Hicks M, et al. Proposed new diagnostic criteria for complex regional pain syndrome. Pain Med. 2007 May-Jun;8(4):326-31. http://www.ncbi.nlm.nih.gov/pubmed/17610454?tool=bestpractice.com [3]Goebel A, Birklein F, Brunner F, et al. The Valencia consensus-based adaptation of the IASP complex regional pain syndrome diagnostic criteria. Pain. 2021 Sep 1;162(9):2346-8. https://journals.lww.com/pain/Fulltext/2021/09000/The_Valencia_consensus_based_adaptation_of_the.5.aspx http://www.ncbi.nlm.nih.gov/pubmed/33729210?tool=bestpractice.com ​​

The patient has continuing pain disproportionate to any inciting event.

At least 1 symptom in 3 of the 4 following categories.

• Sensory: hyperesthesia and/or allodynia.

• Vasomotor: temperature asymmetry and/or skin color changes and/or skin color asymmetry.

• Sudomotor/edema: edema and/or sweating changes and/or sweating asymmetry.

• Motor/trophic: decreased range of motion and/or motor dysfunction (weakness, tremor, dystonia) and/or trophic changes (hair, nail, skin).

Plus at least 1 sign at time of evaluation in 2 or more of the following categories.

• Sensory: hyperalgesia (to pinprick) and/or allodynia (to light touch and/or deep somatic pressure and/or joint movement).

• Vasomotor: temperature asymmetry and/or skin color changes and/or asymmetry.

• Sudomotor/edema: edema and/or sweating changes and/or sweating asymmetry.

• Motor/trophic: decreased range of motion and/or motor dysfunction (weakness, tremor, dystonia) and/or trophic changes (hair, nail, skin).

No other diagnosis to explain the signs and symptoms.

For research purposes there must be at least 1 symptom in all 4 symptom categories, and at least 1 sign in 2 or more sign categories.