History and exam

Key diagnostic factors

common

vesicles/bullae

Seen in bullous impetigo. They are 2 cm in diameter or larger and initially clear, subsequently becoming turbid. Buccal mucosa may be involved.[Figure caption and citation for the preceding image starts]: Neonate with bullous impetigoFrom the collection of Michael Freeman; used with permission [Citation ends].com.bmj.content.model.Caption@1049400d[Figure caption and citation for the preceding image starts]: Florid bullous impetigoFrom the collection of Michael Freeman; used with permission [Citation ends].com.bmj.content.model.Caption@68d5ced0

crusting

Impetigo usually presents a classic facial yellowish to golden crusting. The streptococcal form tends to have thicker and darker crusts.

In resolving impetigo, the crusts usually dry and separate, leaving an erythematous base. [Figure caption and citation for the preceding image starts]: Impetigo of arm presenting as an erosionFrom the collection of Michael Freeman; used with permission [Citation ends].com.bmj.content.model.Caption@1f8fe122

Other diagnostic factors

common

erythema

Patients often present with erosions that have a yellowish to golden crust on an erythematous base.

In resolving impetigo, the crusts usually dry and separate, leaving an erythematous base. [Figure caption and citation for the preceding image starts]: Facial impetigo, yellow crust no longer visibleFrom the collection of Michael Freeman; used with permission [Citation ends].com.bmj.content.model.Caption@7bfe6df5[Figure caption and citation for the preceding image starts]: Impetigo of arm presenting as an erosionFrom the collection of Michael Freeman; used with permission [Citation ends].com.bmj.content.model.Caption@61a01175

uncommon

pruritus

Occasionally pruritic.

pain

Rarely painful.

mucopurulent exudate

In nonhealing cases, there is elevation of the crust by the underlying mucopurulent exudate of active disease.

lymphadenopathy

May occur with severe disease when large areas are affected.

fever

May occur with severe disease when large areas are affected.

Risk factors

strong

increased humidity

During the summer months, increased humidity can increase the likelihood of microtrauma and thus the risk of impetigo.[9][11]

poor hygiene, malnutrition, and overcrowding

These factors promote increased bacterial skin colonization.[9][10]

chronic colonization with Staphylococcus aureus - nasal, axillary, pharyngeal, perineal

The anterior nares of up to 50% of children in a population may be colonized by S aureus.[9] The other noted sites of possible colonization are less frequently involved. Recurrent episodes of impetigo can occur in people colonized by S aureus. Some of these individuals can be a point source for the spread of impetigo.

concomitant skin disease

Skin conditions such as scabies, pediculosis capitis (head lice), and atopic eczema result in destruction of the epidermal barriers, allowing the bacteria easy access in order to establish infection.[7][9][14]

Use of this content is subject to our disclaimer