Epidemiology

The prevalence of peripheral arterial disease (PAD) increases with age, beginning after 40 years of age.[2][3]​ According to the Centers for Disease Control and Prevention, PAD, as defined by abnormal ankle-brachial index of <0.90, was prevalent in 1.0% among a 40- to 49-year-old population. However, with increasing age the prevalence increased. CDC: peripheral arterial disease fact sheet Opens in new window In the age group of 50-59 years the prevalence was around 3.0% to 5.0%, in the age group of 60-69 years it was around 5.0%, and in those over the age of 80 years it was >20.0% (and even >25.0% in men).

The prevalence is similar in the US to the rate in other developed countries. Of note, African-Americans have a higher prevalence of PAD, even after accounting for other risk factors.[4]

In high-income countries, the prevalence of PAD is equal between women and men.[5][6]​ PAD is often under-recognized and undertreated and is a global public health issue.[3][5][7] The impact on patients' lives cannot be overstated.[8]

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