Hip fractures carry an approximately 30% risk of mortality at 1 year, and 25% to 75% of community-dwelling adults may not regain their prefracture level of function.[31]North American Menopause Society. Management of osteoporosis in postmenopausal women: the 2021 position statement of the North American Menopause Society. Menopause. 2021 Sep 1;28(9):973-97.
http://www.ncbi.nlm.nih.gov/pubmed/34448749?tool=bestpractice.com
[134]Magaziner J, Simonsick EM, Kashner TM, et al. Predictors of functional recovery one year following hospital discharge for hip fracture: a prospective study. J Gerontol. 1990 May;45(3):M101-7.
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[135]Fredman L, Hawkes WG, Black S, et al. Elderly patients with hip fracture with positive affect have better functional recovery over 2 years. J Am Geriatr Soc. 2006 Jul;54(7):1074-81.
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[136]Thorngren KG. Fractures in the elderly. Acta Orthop Scand Suppl. 1995 Oct;266:208-10.
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[137]Thorngren KG. Fractures in older persons. Disabil Rehabil.1994 Jul-Sep;16(3):119-26.
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[138]Borgquist L, Ceder L, Thorngren KG. Function and social status 10 years after hip fracture. Prospective follow-up of 103 patients. Acta Orthop Scand. 1990 Oct;61(5):404-10.
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[139]Marottoli RA, Berkman LF, Cooney LM Jr. Decline in physical function following hip fracture. J Am Geriatr Soc. 1992 Sep;40(9):861-6.
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However, for some of the most vulnerable patients with hip fractures (i.e., nursing home residents), the 6-month mortality is as high as 36% (and 46% for men).[17]American Academy of Orthopaedic Surgeons. Management of hip fractures in older adults: evidence-based clinical practice guideline. December 2021 [internet publication].
https://www.aaos.org/globalassets/quality-and-practice-resources/hip-fractures-in-the-elderly/hipfxcpg.pdf
Predictors of mortality include significant comorbid disease, low pre-injury cognitive function, abnormal preoperative ECG, age >85 years, and decreased prefracture mobility.[140]Marottoli RA, Berkman LF, Leo-Summers L, et al. Predictors of mortality and institutionalization after hip fracture: the New Haven EPESE (Established Populations for Epidemiologic Studies of the Elderly) cohort. Am J Public Health. 1994 Nov;84(11):1807-12.
http://ajph.aphapublications.org/doi/pdf/10.2105/AJPH.84.11.1807
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[141]Smith T, Pelpola K, Ball M, et al. Pre-operative indicators for mortality following hip fracture surgery: a systematic review and meta-analysis. Age Ageing. 2014 Jul;43(4):464-71.
https://academic.oup.com/ageing/article/43/4/464/2812257/Pre-operative-indicators-for-mortality-following
http://www.ncbi.nlm.nih.gov/pubmed/24895018?tool=bestpractice.com
Meta-analyses have suggested that early surgery is associated with reduced mortality and complications.[63]Simunovic N, Devereaux PJ, Sprague S, et al. Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ. 2010 Oct 19;182(15):1609-16.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952007
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[64]Moja L, Piatti A, Pecoraro V, et al. Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes - a meta-analysis and meta-regression of over 190,000 patients. PLoS One. 2012;7(10):e46175.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463569
http://www.ncbi.nlm.nih.gov/pubmed/23056256?tool=bestpractice.com
Patients with a positive affect who are in good health and live with someone have a better prognosis.[134]Magaziner J, Simonsick EM, Kashner TM, et al. Predictors of functional recovery one year following hospital discharge for hip fracture: a prospective study. J Gerontol. 1990 May;45(3):M101-7.
http://www.ncbi.nlm.nih.gov/pubmed/2335719?tool=bestpractice.com
[138]Borgquist L, Ceder L, Thorngren KG. Function and social status 10 years after hip fracture. Prospective follow-up of 103 patients. Acta Orthop Scand. 1990 Oct;61(5):404-10.
http://www.ncbi.nlm.nih.gov/pubmed/2239162?tool=bestpractice.com
Older age, frailty, and increasing length of hospital stay result in a poorer prognosis and outcome with respect to return to prefracture functional status.[134]Magaziner J, Simonsick EM, Kashner TM, et al. Predictors of functional recovery one year following hospital discharge for hip fracture: a prospective study. J Gerontol. 1990 May;45(3):M101-7.
http://www.ncbi.nlm.nih.gov/pubmed/2335719?tool=bestpractice.com
[142]van de Ree CLP, Landers MJF, Kruithof N, et al. Effect of frailty on quality of life in elderly patients after hip fracture: a longitudinal study. BMJ Open. 2019 Jul 18;9(7):e025941.
https://bmjopen.bmj.com/content/9/7/e025941.long
http://www.ncbi.nlm.nih.gov/pubmed/31324679?tool=bestpractice.com
One retrospective cohort study showed that nursing home residents with hip fractures and advanced dementia had a lower mortality rate when treated surgically compared with those who were managed nonsurgically, highlighting the need to balance expected outcomes alongside patient goals of care and comorbidities.[143]Berry SD, Rothbaum RR, Kiel DP, et al. Association of clinical outcomes with surgical repair of hip fracture vs nonsurgical management in nursing home residents with advanced dementia. JAMA Intern Med. 2018 Jun 1;178(6):774-80.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997966
http://www.ncbi.nlm.nih.gov/pubmed/29801122?tool=bestpractice.com