Prognosis
This benign disease follows a progressive improving course while medically treated. Since the introduction of bromocriptine in the 1970s into the treatment of prolactinomas, the course of this condition has changed and the prognosis has improved. Today, even when large invasive macroadenomas or giant prolactinomas are diagnosed with chiasmal compression and bilateral temporal hemianopia, continuous treatment with relatively large doses of dopamine agonists will result in prolactin normalization, tumor shrinkage or disappearance, and rapid visual improvement.[34] In some patients, dopamine agonist treatment may be withdrawn after several years without tumor recurrence.[28]
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