Prognosis

Prognosis is generally good. Most patients have resolution of hyperthyroidism following treatment. About 45% to 75% of patients are euthyroid several years following I-131 therapy.[56] However, both surgery and radioactive iodine therapy[57] confer a moderate long-term risk of hypothyroidism.

Nodule size may eventually be reduced by about 45% to 70%.[39][40][41] Much of this reduction occurs during the first 3 months after therapy.[40]

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