Epidemiology
In the US, toxic adenomas are most common in younger adults (age 20 to 40 years) and account for about 5% of cases of hyperthyroidism.[3] Thyrotoxicosis develops at a rate of about 4% per year in euthyroid patients with autonomous adenomas.[4] However, this rate depends on several factors, including the size of the adenoma, iodine intake, and age.[4] In iodine-deficient areas, toxic adenomas and toxic nodular goiters are more common causes of hyperthyroidism than is Graves disease.[5] IGN: global scorecard of iodine nutrition in 2021 Opens in new window
Toxic thyroid adenomas in children are rare, and evidence about them is limited.[6]
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