Superficial vein thrombosis (SVT) is thought to be a relatively common condition, but its exact incidence remains to be determined. This is in part due to the lack of studies in a disease previously considered to be relatively benign and self-limiting.
One study on SVT in primary care in the Netherlands reported an incidence rate of 1.3 per 1000 person-years.[4]Geersing GJ, Cazemier S, Rutten F, et al. Incidence of superficial venous thrombosis in primary care and risk of subsequent venous thromboembolic sequelae: a retrospective cohort study performed with routine healthcare data from the Netherlands. BMJ Open. 2018 Apr 20;8(4):e019967.
https://bmjopen.bmj.com/content/8/4/e019967
http://www.ncbi.nlm.nih.gov/pubmed/29678975?tool=bestpractice.com
One multicenter study in France reported an incidence of 0.64 per 1000 person-years for symptomatic, ultrasonography-confirmed SVT.[5]Frappé P, Buchmuller-Cordier A, Bertoletti L, et al. Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community-based study. J Thromb Haemost. 2014 Jun;12(6):831-8.
https://www.jthjournal.org/article/S1538-7836(22)03964-2/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/24679145?tool=bestpractice.com
About 125,000 episodes of SVT a year have been reported in the US.[6]Blumenberg RM, Barton E, Gelfand ML, et al. Occult deep venous thrombosis complicating superficial thrombophlebitis. J Vasc Surg. 1998 Feb;27(2):338-43.
http://www.ncbi.nlm.nih.gov/pubmed/9510288?tool=bestpractice.com
Most studies report a preponderance of women compared with men (50% to 70%), possibly because of the increased prevalence of varicose veins in women.[1]Nasr H, Scriven JM. Superficial thrombophlebitis (superficial venous thrombosis). BMJ. 2015 Jun 22;350:h2039.
http://www.ncbi.nlm.nih.gov/pubmed/26099257?tool=bestpractice.com
[7]Decousus H, Quéré I, Presles E, et al. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. Ann Intern Med. 2010 Feb 16;152(4):218-24.
http://www.ncbi.nlm.nih.gov/pubmed/20157136?tool=bestpractice.com
Incidence increases with age, with a rate of 0.73 per 1000 person-years among those ages below 40 years and 2.95 per 1000 person-years among those ages >80 years in one study.[4]Geersing GJ, Cazemier S, Rutten F, et al. Incidence of superficial venous thrombosis in primary care and risk of subsequent venous thromboembolic sequelae: a retrospective cohort study performed with routine healthcare data from the Netherlands. BMJ Open. 2018 Apr 20;8(4):e019967.
https://bmjopen.bmj.com/content/8/4/e019967
http://www.ncbi.nlm.nih.gov/pubmed/29678975?tool=bestpractice.com
SVT is generally believed to be more common than deep vein thrombosis, which has an estimated incidence ranging from 88 to 112 per 100 000 person-years.[1]Nasr H, Scriven JM. Superficial thrombophlebitis (superficial venous thrombosis). BMJ. 2015 Jun 22;350:h2039.
http://www.ncbi.nlm.nih.gov/pubmed/26099257?tool=bestpractice.com
[8]Chopard R, Albertsen IE, Piazza G. Diagnosis and treatment of lower extremity venous thromboembolism: a review. JAMA. 2020 Nov 3;324(17):1765-76.
http://www.ncbi.nlm.nih.gov/pubmed/33141212?tool=bestpractice.com