The reasons for screening patients for alcohol use include identifying problem drinkers, and prevention of progression of alcohol abuse and related medical complications.
Screening tools
Patients should be screened for alcohol use disorder (AUD) using a formal assessment tool such as AUDIT-C (Alcohol Use Disorders Identification Test - Consumption), FAST (Fast Alcohol Screening Test), or CAGE.[9]Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.
http://www.ncbi.nlm.nih.gov/pubmed/29301420?tool=bestpractice.com
[43]Crabb DW, Im GY, Szabo G, et al. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2020 Jan;71(1):306-33.
https://www.doi.org/10.1002/hep.30866
http://www.ncbi.nlm.nih.gov/pubmed/31314133?tool=bestpractice.com
Alcohol use disorders identification test consumption (AUDIT C)
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Fast Alcohol Screening Test (FAST)
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CAGE questionnaire
Opens in new window The full AUDIT (Alcohol Use Disorders Identification Test) may also be used, but it takes longer to perform than the other screening tools and therefore may not be suitable in an acute hospital setting.[9]Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.
http://www.ncbi.nlm.nih.gov/pubmed/29301420?tool=bestpractice.com
[43]Crabb DW, Im GY, Szabo G, et al. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2020 Jan;71(1):306-33.
https://www.doi.org/10.1002/hep.30866
http://www.ncbi.nlm.nih.gov/pubmed/31314133?tool=bestpractice.com
[57]Victor M, Adams RD. The effect of alcohol on the nervous system. Res Publ Assoc Res Nerv Ment Dis. 1953;32:526-73.
http://www.ncbi.nlm.nih.gov/pubmed/13134661?tool=bestpractice.com
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) recommends an initial one-question screen to identify potential alcohol use disorder, which is: “How many times in the past year have you had X or more drinks in a day?,” where X is 5 for men and 4 for women.[9]Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.
http://www.ncbi.nlm.nih.gov/pubmed/29301420?tool=bestpractice.com
[43]Crabb DW, Im GY, Szabo G, et al. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2020 Jan;71(1):306-33.
https://www.doi.org/10.1002/hep.30866
http://www.ncbi.nlm.nih.gov/pubmed/31314133?tool=bestpractice.com
[44]Willenbring ML, Massey SH, Gardner MB. Helping patients who drink too much: an evidence-based guide for primary care clinicians. Am Fam Physician. 2009 Jul 1;80(1):44-50.
https://www.aafp.org/pubs/afp/issues/2009/0701/p44.html
http://www.ncbi.nlm.nih.gov/pubmed/19621845?tool=bestpractice.com
This test is positive if the patient’s response is >1, and a formal assessment tool such as AUDIT should then be used.[9]Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.
http://www.ncbi.nlm.nih.gov/pubmed/29301420?tool=bestpractice.com
[43]Crabb DW, Im GY, Szabo G, et al. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2020 Jan;71(1):306-33.
https://www.doi.org/10.1002/hep.30866
http://www.ncbi.nlm.nih.gov/pubmed/31314133?tool=bestpractice.com
[44]Willenbring ML, Massey SH, Gardner MB. Helping patients who drink too much: an evidence-based guide for primary care clinicians. Am Fam Physician. 2009 Jul 1;80(1):44-50.
https://www.aafp.org/pubs/afp/issues/2009/0701/p44.html
http://www.ncbi.nlm.nih.gov/pubmed/19621845?tool=bestpractice.com
Alcohol screening may be difficult to perform in a busy clinical setting (e.g., emergency department) due to limited resources and/or lack of time. Simple screening tools such as CAGE and FAST (4 questions) can be performed in around 12 seconds, while AUDIT (10 questions) requires up to 78 seconds to perform.[81]Williams N. The FAST questionnaire. Occup Med (Lond). 2014 Oct;64(7):559-60.
https://academic.oup.com/occmed/article/64/7/559/1367378
http://www.ncbi.nlm.nih.gov/pubmed/25281578?tool=bestpractice.com
It is important, therefore, to select the appropriate screening tool for clinical application.
Patients who have tested positive for AUD and are at risk of alcohol withdrawal should have their degree of alcohol dependence assessed using a formal screening tool such as the Severity of Alcohol Dependence Questionnaire or the Leeds Dependence Questionnaire.[9]Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.
http://www.ncbi.nlm.nih.gov/pubmed/29301420?tool=bestpractice.com
[45]Raistrick D, Bradshaw J, Tober G, et al. Development of the Leeds Dependence Questionnaire (LDQ): a questionnaire to measure alcohol and opiate dependence in the context of a treatment evaluation package. Addiction. 1994 May;89(5):563-72.
http://www.ncbi.nlm.nih.gov/pubmed/8044122?tool=bestpractice.com
[46]Stockwell T, Hodgson R, Edwards G, et al. The development of a questionnaire to measure severity of alcohol dependence. Br J Addict Alcohol Other Drugs. 1979 Mar;74(1):79-87.
http://www.ncbi.nlm.nih.gov/pubmed/283831?tool=bestpractice.com
[47]Bråthen G, Ben-Menachem E, Brodtkorb E, et al. EFNS guideline on the diagnosis and management of alcohol-related seizures: report of an EFNS task force. Eur J Neurol. 2005 Aug;12(8):575-81.
https://www.doi.org/10.1111/j.1468-1331.2005.01247.x
http://www.ncbi.nlm.nih.gov/pubmed/16053464?tool=bestpractice.com
[82]Ewing JA. Detecting alcoholism. The CAGE questionnaire. JAMA. 1984 Oct 12;252(14):1905-7.
http://www.ncbi.nlm.nih.gov/pubmed/6471323?tool=bestpractice.com
AUDIT-C, FAST, CAGE, and AUDIT only identify alcohol use disorder and do not predict which patients are at risk of alcohol withdrawal.
Patients with a reduced conscious level, and unable to be screened by the above methods, should be monitored for clinical signs of alcohol withdrawal.[5]American Society of Addiction Medicine. The ASAM clinical practice guideline on alcohol withdrawal management. J Addict Med. 2020 May/Jun;14(3s suppl 1):1-72.
https://www.doi.org/10.1097/ADM.0000000000000668
http://www.ncbi.nlm.nih.gov/pubmed/32511109?tool=bestpractice.com
Patients in the intensive care unit who are suspected to be dependent on alcohol should receive prophylactic treatment for alcohol withdrawal.[5]American Society of Addiction Medicine. The ASAM clinical practice guideline on alcohol withdrawal management. J Addict Med. 2020 May/Jun;14(3s suppl 1):1-72.
https://www.doi.org/10.1097/ADM.0000000000000668
http://www.ncbi.nlm.nih.gov/pubmed/32511109?tool=bestpractice.com